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Bicuspid Aortic Valve and Aortopathy

  • Sri Harsha Patlolla
  • Hartzell V. SchaffEmail author
Chapter
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Abstract

Bicuspid aortic valve (BAV) disease is a common valvular malformation found in 1–2% of the general population and is the underlying cause of aortic valve surgery in up to one third of patients in the United States. It is associated with nonvalvular cardiovascular abnormalities, such as aortic coarctation and dilatation of the ascending aorta and aortic sinuses. In general, surgical patients with BAV are younger than patients with tricuspid aortic valves undergoing aortic valve replacement. Similarly, ascending aortopathy associated with BAV becomes manifest at an earlier age than in patients with degenerative aortic disease. This chapter focuses on the current knowledge regarding the BAV and associated aortopathy.

Keywords

Aortic regurgitation Aortic stenosis Aortopathy Ascending aortic aneurysm Bicuspid aortic valve 

Notes

Acknowledgements

This work was supported by the Paul and Ruby Tsai Family.

Disclosures: None.

References

  1. 1.
    Braverman AC, Güven H, Beardslee MA, Makan M, Kates AM, Moon MR. The bicuspid aortic valve. Curr Probl Cardiol. 2005;30:470–522.PubMedCrossRefPubMedCentralGoogle Scholar
  2. 2.
    Fedak PWM, Verma S, David TE, Leask RL, Weisel RD, Butany J. Clinical and pathophysiological implications of a bicuspid aortic valve. Circulation. 2002;106:900–4.PubMedCrossRefPubMedCentralGoogle Scholar
  3. 3.
    Ward C. Clinical significance of the bicuspid aortic valve. Heart. 2000;83:81–5.PubMedPubMedCentralCrossRefGoogle Scholar
  4. 4.
    Roberts WC. The congenitally bicuspid aortic valve. A study of 85 autopsy cases. Am J Cardiol. 1970;26:72–83.PubMedCrossRefPubMedCentralGoogle Scholar
  5. 5.
    Larson EW, Edwards WD. Risk factors for aortic dissection: a necropsy study of 161 cases. Am J Cardiol. 1984;53:849–55.PubMedCrossRefPubMedCentralGoogle Scholar
  6. 6.
    Osler W. The bicuspid condition of the aortic valves. Trans Assoc Am Phys. 1886;2:185–92.Google Scholar
  7. 7.
    Basso C, Boschello M, Perrone C, Mecenero A, Cera A, Bicego D, et al. An echocardiographic survey of primary school children for bicuspid aortic valve. Am J Cardiol. 2004;93:661–3.PubMedCrossRefPubMedCentralGoogle Scholar
  8. 8.
    Huntington K, Hunter AG, Chan KL. A prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve. J Am Coll Cardiol. 1997;30:1809–12.PubMedCrossRefPubMedCentralGoogle Scholar
  9. 9.
    Cripe L, Andelfinger G, Martin LJ, Shooner K, Benson DW. Bicuspid aortic valve is heritable. J Am Coll Cardiol. 2004;44:138–43.PubMedCrossRefPubMedCentralGoogle Scholar
  10. 10.
    Loscalzo ML, Goh DLM, Loeys B, Kent KC, Spevak PJ, Dietz HC. Familial thoracic aortic dilation and bicommissural aortic valve: a prospective analysis of natural history and inheritance. Am J Med Genet A. 2007;143A:1960–7.PubMedCrossRefPubMedCentralGoogle Scholar
  11. 11.
    Michelena HI, Desjardins VA, Avierinos J-F, Russo A, Nkomo VT, Sundt TM, et al. Natural history of asymptomatic patients with normally functioning or minimally dysfunctional bicuspid aortic valve in the community. Circulation. 2008;117:2776–84.PubMedPubMedCentralCrossRefGoogle Scholar
  12. 12.
    Tzemos N, Therrien J, Yip J, Thanassoulis G, Tremblay S, Jamorski MT, et al. Outcomes in adults with bicuspid aortic valves. JAMA. 2008;300:1317–25.PubMedCrossRefPubMedCentralGoogle Scholar
  13. 13.
    Fernandes SM, Sanders SP, Khairy P, Jenkins KJ, Gauvreau K, Lang P, et al. Morphology of bicuspid aortic valve in children and adolescents. J Am Coll Cardiol. 2004;44:1648–51.PubMedCrossRefPubMedCentralGoogle Scholar
  14. 14.
    Michelena HI, Prakash SK, Della Corte A, Bissell MM, Anavekar N, Mathieu P, et al. Bicuspid aortic valve: identifying knowledge gaps and rising to the challenge from the International Bicuspid Aortic Valve Consortium (BAVCon). Circulation. 2014;129:2691–704.PubMedPubMedCentralCrossRefGoogle Scholar
  15. 15.
    Sachdev V, Matura LA, Sidenko S, Ho VB, Arai AE, Rosing DR, et al. Aortic valve disease in Turner syndrome. J Am Coll Cardiol. 2008;51:1904–9.PubMedCrossRefPubMedCentralGoogle Scholar
  16. 16.
    Roche KJ, Genieser NB, Ambrosino MM, Henry GL. MR findings in Shone’s complex of left heart obstructive lesions. Pediatr Radiol. 1998;28:841–5.PubMedCrossRefPubMedCentralGoogle Scholar
  17. 17.
    Roos-Hesselink JW, Schölzel BE, Heijdra RJ, Spitaels SEC, Meijboom FJ, Boersma E, et al. Aortic valve and aortic arch pathology after coarctation repair. Heart. 2003;89:1074–7.PubMedPubMedCentralCrossRefGoogle Scholar
  18. 18.
    Tribouilloy C, Rusinaru D, Sorel C, Thuny F, Casalta J-P, Riberi A, et al. Clinical characteristics and outcome of infective endocarditis in adults with bicuspid aortic valves: a multicentre observational study. Heart. 2010;96:1723–9.PubMedCrossRefPubMedCentralGoogle Scholar
  19. 19.
    Verma S, Siu SC. Aortic dilatation in patients with bicuspid aortic valve. N Engl J Med. 2014;370:1920–9.PubMedCrossRefPubMedCentralGoogle Scholar
  20. 20.
    Siu SC, Silversides CK. Bicuspid aortic valve disease. J Am Coll Cardiol. 2010;55:2789–800.PubMedCrossRefPubMedCentralGoogle Scholar
  21. 21.
    Sievers H-H, Schmidtke C. A classification system for the bicuspid aortic valve from 304 surgical specimens. J Thorac Cardiovasc Surg. 2007;133:1226–33.CrossRefGoogle Scholar
  22. 22.
    Sabet HY, Edwards WD, Tazelaar HD, Daly RC. Congenitally bicuspid aortic valves: a surgical pathology study of 542 cases (1991 through 1996) and a literature review of 2,715 additional cases. Mayo Clin Proc. 1999;74:14–26.PubMedCrossRefPubMedCentralGoogle Scholar
  23. 23.
    Kappetein AP, Gittenberger-de Groot AC, Zwinderman AH, Rohmer J, Poelmann RE, Huysmans HA. The neural crest as a possible pathogenetic factor in coarctation of the aorta and bicuspid aortic valve. J Thorac Cardiovasc Surg. 1991;102:830–6.PubMedCrossRefPubMedCentralGoogle Scholar
  24. 24.
    Fernández B, Durán AC, Fernández-Gallego T, Fernández MC, Such M, Arqué JM, et al. Bicuspid aortic valves with different spatial orientations of the leaflets are distinct etiological entities. J Am Coll Cardiol. 2009;54:2312–8.PubMedCrossRefPubMedCentralGoogle Scholar
  25. 25.
    Lee TC, Zhao YD, Courtman DW, Stewart DJ. Abnormal aortic valve development in mice lacking endothelial nitric oxide synthase. Circulation. 2000;101:2345–8.PubMedCrossRefPubMedCentralGoogle Scholar
  26. 26.
    Aicher D, Urbich C, Zeiher A, Dimmeler S, Schäfers H-J. Endothelial nitric oxide synthase in bicuspid aortic valve disease. Ann Thorac Surg. 2007;83:1290–4.PubMedCrossRefPubMedCentralGoogle Scholar
  27. 27.
    Eisenberg LM, Markwald RR. Molecular regulation of atrioventricular valvuloseptal morphogenesis. Circ Res. 1995;77:1–6.PubMedCrossRefPubMedCentralGoogle Scholar
  28. 28.
    Ayad RF, Grayburn PA, Ko JM, Filardo G, Roberts WC. Accuracy of two-dimensional echocardiography in determining aortic valve structure in patients >50 years of age having aortic valve replacement for aortic stenosis. Am J Cardiol. 2011;108:1589–99.PubMedCrossRefPubMedCentralGoogle Scholar
  29. 29.
    Roberts WC, Vowels TJ, Ko JM. Natural history of adults with congenitally malformed aortic valves (unicuspid or bicuspid). Medicine. 2012;91:287–308.PubMedCrossRefPubMedCentralGoogle Scholar
  30. 30.
    Mohler ER 3rd. Are atherosclerotic processes involved in aortic-valve calcification? Lancet. 2000;356:524–5.PubMedCrossRefPubMedCentralGoogle Scholar
  31. 31.
    Chan KL, Ghani M, Woodend K, Burwash IG. Case-controlled study to assess risk factors for aortic stenosis in congenitally bicuspid aortic valve. Am J Cardiol. 2001;88:690–3.PubMedCrossRefPubMedCentralGoogle Scholar
  32. 32.
    Roberts WC, Ko JM. Frequency by decades of unicuspid, bicuspid, and tricuspid aortic valves in adults having isolated aortic valve replacement for aortic stenosis, with or without associated aortic regurgitation. Circulation. 2005;111:920–5.PubMedCrossRefPubMedCentralGoogle Scholar
  33. 33.
    Awadallah SM, Kavey R-EW, Byrum CJ, Smith FC, Kveselis DA, Blackman MS. The changing pattern of infective endocarditis in childhood. Am J Cardiol. 1991;68:90–4.PubMedCrossRefPubMedCentralGoogle Scholar
  34. 34.
    Braverman AC. Aortic involvement in patients with a bicuspid aortic valve. Heart. 2011;97:506–13.PubMedCrossRefPubMedCentralGoogle Scholar
  35. 35.
    Girdauskas E, Borger MA, Secknus M-A, Girdauskas G, Kuntze T. Is aortopathy in bicuspid aortic valve disease a congenital defect or a result of abnormal hemodynamics? A critical reappraisal of a one-sided argument. Eur J Cardiothorac Surg. 2011;39:809–14.PubMedCrossRefPubMedCentralGoogle Scholar
  36. 36.
    Hope MD, Hope TA, Meadows AK, Ordovas KG, Urbania TH, Alley MT, et al. Bicuspid aortic valve: four-dimensional MR evaluation of ascending aortic systolic flow patterns. Radiology. 2010;255:53–61.PubMedCrossRefPubMedCentralGoogle Scholar
  37. 37.
    Vergara C, Viscardi F, Antiga L, Luciani GB. Influence of bicuspid valve geometry on ascending aortic fluid dynamics: a parametric study. Artif Organs. 2012;36:368–78.PubMedCrossRefPubMedCentralGoogle Scholar
  38. 38.
    Viscardi F, Vergara C, Antiga L, Merelli S, Veneziani A, Puppini G, et al. Comparative finite element model analysis of ascending aortic flow in bicuspid and tricuspid aortic valve. Artif Organs. 2010;34:1114–20.PubMedCrossRefPubMedCentralGoogle Scholar
  39. 39.
    Michelena HI, Khanna AD, Mahoney D, Margaryan E, Topilsky Y, Suri RM, et al. Incidence of aortic complications in patients with bicuspid aortic valves. JAMA. 2011;306:1104–12.PubMedCrossRefPubMedCentralGoogle Scholar
  40. 40.
    Spittell PC, Spittell JA Jr, Joyce JW, Tajik AJ, Edwards WD, Schaff HV, et al. Clinical features and differential diagnosis of aortic dissection: experience with 236 cases (1980 through 1990). Mayo Clin Proc. 1993;68:642–51.PubMedCrossRefPubMedCentralGoogle Scholar
  41. 41.
    Oliver JM, Gallego P, Gonzalez A, Aroca A, Bret M, Mesa JM. Risk factors for aortic complications in adults with coarctation of the aorta. J Am Coll Cardiol. 2004;44:1641–7.PubMedCrossRefPubMedCentralGoogle Scholar
  42. 42.
    Oliver JM, Alonso-Gonzalez R, Gonzalez AE, Gallego P, Sanchez-Recalde A, Cuesta E, et al. Risk of aortic root or ascending aorta complications in patients with bicuspid aortic valve with and without coarctation of the aorta. Am J Cardiol. 2009;104:1001–6.PubMedCrossRefPubMedCentralGoogle Scholar
  43. 43.
    Cohen M, Fuster V, Steele PM, Driscoll D, McGoon DC. Coarctation of the aorta. Long-term follow-up and prediction of outcome after surgical correction. Circulation. 1989;80:840–5.PubMedCrossRefPubMedCentralGoogle Scholar
  44. 44.
    Warnes CA, Williams RG, Bashore TM, Child JS, Connolly HM, Dearani JA, et al. ACC/AHA 2008 guidelines for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Develop Guidelines on the Management of Adults With Congenital Heart Disease). Developed in Collaboration With the American Society of Echocardiography, Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol. 2008;52:e143–263.PubMedCrossRefPubMedCentralGoogle Scholar
  45. 45.
    Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP 3rd, Guyton RA, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014;63:e57–185.CrossRefGoogle Scholar
  46. 46.
    Schneider U, Schmied W, Aicher D, Giebels C, Winter L, Schäfers H-J. Sinus plication to improve valve configuration in bicuspid aortic valve repair-early results. Ann Thorac Surg. 2017;103:580–5.PubMedCrossRefPubMedCentralGoogle Scholar
  47. 47.
    Schneider U, Hofmann C, Aicher D, Takahashi H, Miura Y, Schäfers H-J. Suture annuloplasty significantly improves the durability of bicuspid aortic valve repair. Ann Thorac Surg. 2017;103:504–10.PubMedCrossRefPubMedCentralGoogle Scholar
  48. 48.
    Svensson LG, Al Kindi AH, Vivacqua A, Pettersson GB, Gillinov AM, Mihaljevic T, et al. Long-term durability of bicuspid aortic valve repair. Ann Thorac Surg. 2014;97:1539–47.PubMedCrossRefPubMedCentralGoogle Scholar
  49. 49.
    Sharma V, Suri RM, Dearani JA, Burkhart HM, Park SJ, Joyce LD, et al. Expanding relevance of aortic valve repair—is earlier operation indicated? J Thorac Cardiovasc Surg. 2014;147:100–7.PubMedCrossRefPubMedCentralGoogle Scholar
  50. 50.
    Ashikhmina E, Sundt TM 3rd, Dearani JA, Connolly HM, Li Z, Schaff HV. Repair of the bicuspid aortic valve: a viable alternative to replacement with a bioprosthesis. J Thorac Cardiovasc Surg. 2010;139:1395–401.PubMedCrossRefPubMedCentralGoogle Scholar
  51. 51.
    Bauer T, Linke A, Sievert H, Kahlert P, Hambrecht R, Nickenig G, et al. Comparison of the effectiveness of transcatheter aortic valve implantation in patients with stenotic bicuspid versus tricuspid aortic valves (from the German TAVI Registry). Am J Cardiol. 2014;113:518–21.CrossRefPubMedGoogle Scholar
  52. 52.
    Kochman J, Huczek Z, Scisło P, Dabrowski M, Chmielak Z, Szymański P, et al. Comparison of one- and 12-month outcomes of transcatheter aortic valve replacement in patients with severely stenotic bicuspid versus tricuspid aortic valves (results from a multicenter registry). Am J Cardiol. 2014;114:757–62.PubMedCrossRefPubMedCentralGoogle Scholar
  53. 53.
    Hayashida K, Bouvier E, Lefèvre T, Chevalier B, Hovasse T, Romano M, et al. Transcatheter aortic valve implantation for patients with severe bicuspid aortic valve stenosis. Circ Cardiovasc Interv. 2013;6:284–91.PubMedCrossRefPubMedCentralGoogle Scholar
  54. 54.
    Phan K, Wong S, Phan S, Ha H, Qian P, Yan TD. Transcatheter aortic valve implantation (TAVI) in patients with bicuspid aortic valve stenosis—systematic review and meta-analysis. Heart Lung Circ. 2015;24:649–59.CrossRefPubMedGoogle Scholar
  55. 55.
    Roy DA, Schaefer U, Guetta V, Hildick-Smith D, Möllmann H, Dumonteil N, et al. Transcatheter aortic valve implantation for pure severe native aortic valve regurgitation. J Am Coll Cardiol. 2013;61:1577–84.PubMedCrossRefPubMedCentralGoogle Scholar
  56. 56.
    Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP 3rd, Fleisher LA, et al. 2017 AHA/ACC focused update of the 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2017;70:252–89.PubMedPubMedCentralCrossRefGoogle Scholar
  57. 57.
    Tuna IC, Orszulak TA, Schaff HV, Danielson GK. Results of homograft aortic valve replacement for active endocarditis. Ann Thorac Surg. 1990;49:619–24.PubMedCrossRefPubMedCentralGoogle Scholar
  58. 58.
    Kirklin JK. Challenging homografts as the holy grail for aortic valve endocarditis. J Thorac Cardiovasc Surg. 2016;151:1230–1.PubMedCrossRefPubMedCentralGoogle Scholar
  59. 59.
    Goldstone AB, Chiu P, Baiocchi M, Lingala B, Patrick WL, Fischbein MP, et al. Mechanical or biologic prostheses for aortic-valve and mitral-valve replacement. N Engl J Med. 2017;377:1847–57.PubMedCrossRefPubMedCentralGoogle Scholar
  60. 60.
    Lund O, Bland M. Risk-corrected impact of mechanical versus bioprosthetic valves on long-term mortality after aortic valve replacement. J Thorac Cardiovasc Surg. 2006;132:20–6.PubMedCrossRefPubMedCentralGoogle Scholar
  61. 61.
    Glaser N, Jackson V, Holzmann MJ, Franco-Cereceda A, Sartipy U. Aortic valve replacement with mechanical vs. biological prostheses in patients aged 50-69 years. Eur Heart J. 2016;37:2658–67.PubMedCrossRefPubMedCentralGoogle Scholar
  62. 62.
    Sharabiani MTA, Dorobantu DM, Mahani AS, Turner M, Peter Tometzki AJ, Angelini GD, et al. Aortic valve replacement and the ross operation in children and young adults. J Am Coll Cardiol. 2016;67:2858–70.PubMedCrossRefPubMedCentralGoogle Scholar
  63. 63.
    Schneider AW, Putter H, Klautz RJM, Bruggemans EF, Holman ER, Bökenkamp R, et al. Long-term follow-up after the Ross procedure: a single center 22-year experience. Ann Thorac Surg. 2017;103:1976–83.PubMedCrossRefPubMedCentralGoogle Scholar
  64. 64.
    Ouzounian M, Mazine A, David TE. The Ross procedure is the best operation to treat aortic stenosis in young and middle-aged adults. J Thorac Cardiovasc Surg. 2017;154:778–82.PubMedCrossRefPubMedCentralGoogle Scholar
  65. 65.
    Schaff HV. Ross procedure for aortic valve replacement in young adults: preferred procedure or “double, double toil and trouble”? Circulation. 2016;134:586–8.PubMedCrossRefPubMedCentralGoogle Scholar
  66. 66.
    Stulak JM, Burkhart HM, Sundt TM 3rd, Connolly HM, Suri RM, Schaff HV, et al. Spectrum and outcome of reoperations after the Ross procedure. Circulation. 2010;122:1153–8.PubMedCrossRefPubMedCentralGoogle Scholar
  67. 67.
    Borger MA, Fedak PWM, Stephens EH, Gleason TG, Girdauskas E, Ikonomidis JS, et al. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: executive summary. J Thorac Cardiovasc Surg. 2018;156:473–80.PubMedPubMedCentralCrossRefGoogle Scholar
  68. 68.
    Paruchuri V, Salhab KF, Kuzmik G, Gubernikoff G, Fang H, Rizzo JA, et al. Aortic size distribution in the general population: explaining the size paradox in aortic dissection. Cardiology. 2015;131:265–72.PubMedCrossRefPubMedCentralGoogle Scholar
  69. 69.
    Zafar MA, Li Y, Rizzo JA, Charilaou P, Saeyeldin A, Velasquez CA, et al. Height alone, rather than body surface area, suffices for risk estimation in ascending aortic aneurysm. J Thorac Cardiovasc Surg. 2018;155:1938–50.PubMedCrossRefPubMedCentralGoogle Scholar
  70. 70.
    Davies RR, Gallo A, Coady MA, Tellides G, Botta DM, Burke B, et al. Novel measurement of relative aortic size predicts rupture of thoracic aortic aneurysms. Ann Thorac Surg. 2006;81:169–77.PubMedCrossRefPubMedCentralGoogle Scholar
  71. 71.
    Gravholt CH, Landin-Wilhelmsen K, Stochholm K, Hjerrild BE, Ledet T, Djurhuus CB, et al. Clinical and epidemiological description of aortic dissection in Turner’s syndrome. Cardiol Young. 2006;16:430–6.PubMedCrossRefPubMedCentralGoogle Scholar
  72. 72.
    Lansman SL, Goldberg JB, Kai M, Tang GHL, Malekan R, Spielvogel D. Aortic surgery in pregnancy. J Thorac Cardiovasc Surg. 2017;153:S44–8.PubMedCrossRefPubMedCentralGoogle Scholar
  73. 73.
    Girdauskas E, Rouman M, Disha K, Espinoza A, Misfeld M, Borger MA, et al. Aortic dissection after previous aortic valve replacement for bicuspid aortic valve disease. J Am Coll Cardiol. 2015;66:1409–11.PubMedCrossRefPubMedCentralGoogle Scholar
  74. 74.
    Wang Y, Wu B, Li J, Dong L, Wang C, Shu X. Impact of aortic insufficiency on ascending aortic dilatation and adverse aortic events after isolated aortic valve replacement in patients with a bicuspid aortic valve. Ann Thorac Surg. 2016;101:1707–14.PubMedCrossRefPubMedCentralGoogle Scholar
  75. 75.
    Della Corte A, Bancone C, Quarto C, Dialetto G, Covino FE, Scardone M, et al. Predictors of ascending aortic dilatation with bicuspid aortic valve: a wide spectrum of disease expression. Eur J Cardiothorac Surg. 2007;31:397–404.PubMedCrossRefPubMedCentralGoogle Scholar
  76. 76.
    Della Corte A, Bancone C, Buonocore M, Dialetto G, Covino FE, Manduca S, et al. Pattern of ascending aortic dimensions predicts the growth rate of the aorta in patients with bicuspid aortic valve. JACC Cardiovasc Imaging. 2013;6:1301–10.PubMedCrossRefPubMedCentralGoogle Scholar
  77. 77.
    Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, et al. 2014 ESC guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC). Eur Heart J. 2014;35:2873–926.PubMedCrossRefPubMedCentralGoogle Scholar
  78. 78.
    Vahanian A. Guidelines on the management of valvular heart disease (version 2012) the joint task force of ESC & EACTS. Eur J Cardiothorac Surg. 2012;42:S1–44.PubMedCrossRefPubMedCentralGoogle Scholar
  79. 79.
    Borger MA, Preston M, Ivanov J, Fedak PWM, Davierwala P, Armstrong S, et al. Should the ascending aorta be replaced more frequently in patients with bicuspid aortic valve disease? J Thorac Cardiovasc Surg. 2004;128:677–83.PubMedCrossRefPubMedCentralGoogle Scholar
  80. 80.
    Eleid MF, Forde I, Edwards WD, Maleszewski JJ, Suri RM, Schaff HV, et al. Type A aortic dissection in patients with bicuspid aortic valves: clinical and pathological comparison with tricuspid aortic valves. Heart. 2013;99:1668–74.PubMedCrossRefPubMedCentralGoogle Scholar
  81. 81.
    Svensson LG, Kim K-H, Blackstone EH, Rajeswaran J, Gillinov AM, Mihaljevic T, et al. Bicuspid aortic valve surgery with proactive ascending aorta repair. J Thorac Cardiovasc Surg. 2011;142:622–9. 629.e1–3PubMedCrossRefPubMedCentralGoogle Scholar
  82. 82.
    Etz CD, von Aspern K, Hoyer A, Girrbach FF, Leontyev S, Bakhtiary F, et al. Acute type A aortic dissection: characteristics and outcomes comparing patients with bicuspid versus tricuspid aortic valve. Eur J Cardiothorac Surg. 2015;48:142–50.PubMedCrossRefPubMedCentralGoogle Scholar
  83. 83.
    Ugur M, Schaff HV, Suri RM, Dearani JA, Joyce LD, Greason KL, et al. Late outcome of noncoronary sinus replacement in patients with bicuspid aortic valves and aortopathy. Ann Thorac Surg. 2014;97:1242–6.PubMedCrossRefPubMedCentralGoogle Scholar
  84. 84.
    Peterss S, Charilaou P, Dumfarth J, Li Y, Bhandari R, Tranquilli M, et al. Aortic valve disease with ascending aortic aneurysm: impact of concomitant root-sparing (supracoronary) aortic replacement in nonsyndromic patients. J Thorac Cardiovasc Surg. 2016;152:791–8.e1.PubMedCrossRefPubMedCentralGoogle Scholar
  85. 85.
    Park CB, Greason KL, Suri RM, Michelena HI, Schaff HV, Sundt TM 3rd. Fate of nonreplaced sinuses of Valsalva in bicuspid aortic valve disease. J Thorac Cardiovasc Surg. 2011;142:278–84.PubMedCrossRefPubMedCentralGoogle Scholar
  86. 86.
    Regeer MV, Versteegh MIM, Klautz RJM, Schalij MJ, Bax JJ, Marsan NA, et al. Effect of aortic valve replacement on aortic root dilatation rate in patients with bicuspid and tricuspid aortic valves. Ann Thorac Surg. 2016;102:1981–7.PubMedCrossRefPubMedCentralGoogle Scholar
  87. 87.
    Malaisrie SC, Duncan BF, Mehta CK, Badiwala MV, Rinewalt D, Kruse J, et al. The addition of hemiarch replacement to aortic root surgery does not affect safety. J Thorac Cardiovasc Surg. 2015;150:118–24.e2.PubMedCrossRefPubMedCentralGoogle Scholar
  88. 88.
    Fazel SS, Mallidi HR, Lee RS, Sheehan MP, Liang D, Fleischman D, et al. The aortopathy of bicuspid aortic valve disease has distinctive patterns and usually involves the transverse aortic arch. J Thorac Cardiovasc Surg. 2008;135:901–7. 907.e1–2PubMedCrossRefPubMedCentralGoogle Scholar
  89. 89.
    Park CB, Greason KL, Suri RM, Michelena HI, Schaff HV, Sundt TM 3rd. Should the proximal arch be routinely replaced in patients with bicuspid aortic valve disease and ascending aortic aneurysm? J Thorac Cardiovasc Surg. 2011;142:602–7.PubMedCrossRefPubMedCentralGoogle Scholar
  90. 90.
    Miyata H, Motomura N, Ueda Y, Tsukihara H, Tabayashi K, Takamoto S. Toward quality improvement of thoracic aortic surgery: estimating volume-outcome effect from nationwide survey. Eur J Cardiothorac Surg. 2009;36:517–21.PubMedCrossRefPubMedCentralGoogle Scholar
  91. 91.
    Gazoni LM, Speir AM, Kron IL, Fonner E, Crosby IK. Elective thoracic aortic aneurysm surgery: better outcomes from high-volume centers. J Am Coll Surg. 2010;210:855–9.PubMedCrossRefPubMedCentralGoogle Scholar

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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Cardiovascular SurgeryMayo ClinicRochesterUSA

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