Tissue Sealants in Cardiac Surgery

  • Louis P. PerraultEmail author
  • Fatima Zohra Moukhariq


Significant bleeding is the most common surgical complication, occurring in up to 25% of all surgeries. Bleeding causes increased mortality and morbidity, by increasing the number of transfusions required, secondary to increased cumulative blood loss, and by causing hemodynamic instability. A solution to this issue encountered during surgery is the use of hemostatic products, tissue sealants, and adhesives. Worldwide, the number of topical adhesives, surgical sealants, and hemostats approved for use in the surgical setting is ever expanding. The objectives of this chapter are to review the spectrum of haemostats, sealants and adhesives products available in cardiovascular surgery and to provide an update on new products to be soon available, or in development, for reducing bleeding during surgical procedures.


Adhesives Fibrin sealants Cardiac surgery Hemostatic agents Tissue sealants 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Cardiac Surgery DepartmentMontreal Heart InstituteMontrealCanada
  2. 2.Department of Surgery and PharmacologyUniversité de MontréalMontrealCanada
  3. 3.Research CenterMontreal Heart Institute, Université de MontréalMontrealCanada

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