Urologic Complications of Friedreich’s Ataxia
Friedrich’s ataxia is an early onset hereditary condition that causes progressive neurologic decline. Common urologic symptoms include urinary frequency, urgency, and incontinence. Elevated post-void residuals are also not uncommon. Urodynamic testing may demonstrate detrusor overactivity and detrusor sphincter dyssynergia but usually the bladder compliance is normal. Urologic treatment goals revolve around emptying the bladder completely via intermittent catheterization or indwelling catheter and managing overactive bladder symptoms with medications or onabotulinum injections. Friedrich’s ataxia patients have a potentially high risk of surgical complications due to underlying respiratory weakness and cardiac pathologies.
KeywordsFriedreich’s ataxia Urinary incontinence Urinary frequency Urodynamics Treatment