Advertisement

A Young Man with Hypopigmented Macules on Trunk and Multiple Shiny Nodules Over Face

  • Avijit Mondal
  • Subhash Dasarathan
Chapter
Part of the Clinical Cases in Dermatology book series (CLIDADE)

Abstract

Leprosy (Hansen’s disease) is a chronic infectious disease caused by Mycobacterium leprae, primarily affecting the peripheral nerves, and skin. In persons with high bacillary load (lepromatous pole), the internal organs also may be affected. A 19-year-old male presented to the dermatology OPD with hypopigmented skin lesions on trunk and limbs for 6 months, along with complaints of decreased sensation over both lower legs. Bilateral non-tender thickening of ulnar and common peroneal nerves were noted. Loss of sensation of temperature, touch, and diminished pain perception were elicited in both lower legs along with dryness and loss of hair. Slit skin smear from nodules showed numerous acid fast bacilli occurring singly or in globi. Patient was treated by multidrug therapy (MDT) as per World Health Organization regimen.

Keywords

Peripheral nerve thickening Acid fast bacilli Leprosy Hansen’s disease Mycobacterium leprae 

References

  1. 1.
    Kumar B, Dogra S. Leprosy: a disease with diagnostic and management challenges! Indian J Dermatol Venereol Leprol. 2009;75:111–5.CrossRefGoogle Scholar
  2. 2.
    Kumar P, Savant SS, Das A. A curious case of lepromatous leprosy developing complete loss of pigmentation, followed by reappearance of pigmentation with multi drug therapy (MDT) alone—a support for neural theory of vitiligo pathogenesis? Indian J Lepr. 2018;90:155–9.Google Scholar
  3. 3.
    Madhusudan M. Leprous neuritis: a diagnostic dilemma. Indian J Dermatol Venereol Leprol. 1999;65:59–65.Google Scholar
  4. 4.
    Grzbowski A, Nita M, Virmond M. Ocular leprosy. Clin Dermatol. 2014;33:79–89.CrossRefGoogle Scholar
  5. 5.
    Singh A, Ramesh V. Histopathological features in leprosy, post-kala-azar dermal leishmaniasis, and cutaneous leishmaniasis. Indian J Dermatol Venereol Leprol. 2013;79:360–6.CrossRefGoogle Scholar
  6. 6.
    Arora S, D’Souza P, Haroon MA, Ramesh V, Kaur O, Chandoke RK. Post-kala-azar dermal leishmaniasis mimicking leprosy relapse: a diagnostic dilemma. Int J Dermatol. 2014;53:606–8.CrossRefGoogle Scholar
  7. 7.
    Anand V, Pradhan S, Kumar P. Autonomic neuropathy impairing quality of life after completion of MDT: are we managing enough? Lepr Rev. 2016;87(2):239–42.PubMedGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Avijit Mondal
    • 1
  • Subhash Dasarathan
    • 1
  1. 1.College of Medicine and JNM HospitalKalyaniIndia

Personalised recommendations