Percutaneous Ablation

  • Guojun Qian
  • Jinglei Zhang
  • Feng Shen


Intrahepatic cholangiocarcinoma (ICC) is an aggressive primary hepatic malignancy. While standard therapy for localized disease involves radical resection with regional lymphadenectomy, percutaneous ablative techniques including radiofrequency ablation (RFA) and microwave ablation (MWA) have been used in patients with unresectable recurrent ICC. In addition, limited data are available on the use of ICC for patients with early stage ICC. These treatments have fewer complications compared with hepatectomy.

Several studies have reported optimal long-term survival following ablative treatments. However, current research on these treatments in ICC patients is still limited. Research on treatment indications, comparisons of outcomes following surgical resection versus ablation, and the differences in treatment efficacy between RFA and MWA are relatively immature compared to the evidence available for patients with hepatocellular carcinoma. Nevertheless, emerging data suggest percutaneous ablation is safe, feasible, and an important component in the multidisciplinary care of patients with ICC. In this chapter, we review the technique, mechanism of action, indications, and outcomes of percutaneous ablation for ICC.


Intrahepatic cholangiocarcinoma Radiofrequency ablation Microwave ablation Outcome 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Guojun Qian
    • 1
  • Jinglei Zhang
    • 1
  • Feng Shen
    • 2
  1. 1.Department of Ultrasound Interventional TherapyEastern Hepatobiliary Surgery Hospital, Naval Medical UniversityShanghaiChina
  2. 2.Department of Hepatic SurgeryEastern Hepatobiliary Surgery Hospital, Naval Medical UniversityShanghaiChina

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