Pediatric Acute Respiratory Distress Syndrome in Immunocompromised Patients

  • Courtney M. RowanEmail author


Immunocompromised children are at high risk for both the development of pediatric acute respiratory distress syndrome (PARDS) and PARDS-related mortality. This complex population seems to be growing, and overall critical care outcomes are improving. When the immunocompromised child develops acute hypoxic respiratory failure, careful deliberation for a diagnostic workup must be done, since this population is at risk for both infectious and noninfectious pulmonary complications. Given the risk for severe PARDS, if noninvasive respiratory support strategies are attempted, they should be done so early in the disease course. If invasive mechanical ventilation is applied, a focus should be placed on lung-protective strategies. Throughout the critical illness, it is important to have ongoing multispecialty collaboration and consideration of the status of the underlying immunocompromising condition. We will explore many of these issues in this chapter.


ARDS Immunocompromised host Neoplasms Hematopoietic stem cell transplantation Pediatrics 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Pediatrics, Division of Critical CareIndiana University School of MedicineIndianapolisUSA

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