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Towards the Economic Evaluation of Two Mini-invasive Surgical Techniques for Head&Neck Cancer: A Customizable Model for Different Populations

  • Elisa SalviEmail author
  • Enea Parimbelli
  • Lucia Sacchi
  • Silvana Quaglini
  • Erika Maggi
  • Lorry Duchoud
  • Gian Luca Armas
  • John De Almeida
  • Christian Simon
Conference paper
  • 756 Downloads
Part of the Lecture Notes in Computer Science book series (LNCS, volume 11526)

Abstract

Sometimes representing a decision process involves building multi-stage models, where some outputs of stagei become the inputs of stagei+1. This was the case for an economic evaluation study of two mini-invasive techniques for head&neck cancer, namely Transoral Robotic Surgery and Transoral Laser Microsurgery. We built a two-stage model, composed by a first decision tree ac-counting for the surgical complications and need for additional treatments, which in turn are used as initial conditions for a second decision tree that models long-term outcomes through a Markov process. To allow the automatic concatenation of decision trees, we developed a Java extension to the TreeAgePro software, a well-known tool for decision analysis. Moreover, we integrated the resulting model into UceWeb, a framework we developed over the last two years, which allows personalizing costs and preferences for different target populations. In this way the same model may be re-used to perform cost/utility and cost/effectiveness analysis in different settings.

Keywords

Decision analysis Economic evaluation Head&neck cancer 

References

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Elisa Salvi
    • 1
    Email author
  • Enea Parimbelli
    • 2
  • Lucia Sacchi
    • 1
  • Silvana Quaglini
    • 1
  • Erika Maggi
    • 1
  • Lorry Duchoud
    • 3
  • Gian Luca Armas
    • 3
  • John De Almeida
    • 4
  • Christian Simon
    • 3
  1. 1.University of PaviaPaviaItaly
  2. 2.University of OttawaOttawaCanada
  3. 3.Service d’Oto-rhino-laryngologie - Chirurgie cervico-faciale, Centre Hospitalier Universitaire Vaudois (CHUV)Université de Lausanne (UNIL)LausanneSwitzerland
  4. 4.Otolaryngology-Head and Neck Surgery-Surgical Oncology, Princess Margaret Cancer CentreUniversity of TorontoTorontoCanada

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