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Surgical Treatment of Erectile Dysfunction: Historical Perspective and Overview

  • Afonso Morgado
  • Nuno Tomada
  • Joaquim Sarquella
Chapter

Abstract

In this chapter the surgical treatment of erectile dysfunction and its historical perspective are reviewed. The standard surgical treatment of erectile dysfunction is the implantation of a penile prothesis, either semirigid or inflatable ones. Penile prothesis materials and design have improved along the last three decades, contributing to a lower rate of mechanical complications and an increased long-term durability. Both penile prothesis hydrophilic- and antibiotic impregnated-coatings, as well as new operative approaches such as the “no touch” approach, have greatly contributed to the lower rate of post-operative infection observed in recent years. Surgeons must be aware of both intra- and post-operative complications of penile prothesis implantation and their management as its prevention is key to success. Penile revascularization still has a minor role in the surgical treatment of erectile dysfunction, although patient selection is key.

Keywords

Erectile dysfunction Penile prothesis Semi-rigid Inflatable Erosion Infection Penile revascularization 

References

  1. 1.
    Malenfant J, et al. Francesco Parona (1842-1908) and his contributions to our understanding of surgery through anatomy. Clin Anat. 2013;26(5):547–50.PubMedGoogle Scholar
  2. 2.
    Lue TF. Penile venous surgery. Urol Clin North Am. 1989;16(3):607–11.PubMedGoogle Scholar
  3. 3.
    Lowsley OS, Cangelosi JT. Ten years experience with an operation for the cure of certain types of sexual impotence. South Med J. 1946;39:67–9.PubMedGoogle Scholar
  4. 4.
    Kim ED, McVary KT. Long-term results with penile vein ligation for venogenic impotence. J Urol. 1995;153(3 Pt 1):655–8.PubMedGoogle Scholar
  5. 5.
    Popken G, Katzenwadel A, Wetterauer U. Long-term results of dorsal penile vein ligation for symptomatic treatment of erectile dysfunction. Andrologia. 1999;31(Suppl 1):77–82.PubMedGoogle Scholar
  6. 6.
    Da Ros CT, et al. Long-term results of penile vein ligation for erectile dysfunction due to cavernovenous disease. Tech Urol. 2000;6(3):172–4.PubMedGoogle Scholar
  7. 7.
    Schultheiss D, Gabouev AI, Jonas U, Bogoraz NA. (1874-1952): pioneer of phalloplasty and penile implant surgery. J Sex Med. 2005;2(1):139–46.PubMedGoogle Scholar
  8. 8.
    Le B, Burnett AL. Evolution of penile prosthetic devices. Korean J Urol. 2015;56(3):179–86.PubMedPubMedCentralGoogle Scholar
  9. 9.
    Carrion H, et al. A history of the penile implant to 1974. Sex Med Rev. 2016;4(3):285–93.PubMedGoogle Scholar
  10. 10.
    Rodriguez KM, Pastuszak AW. A history of penile implants. Transl Androl Urol. 2017;6(Suppl 5):S851–7.PubMedPubMedCentralGoogle Scholar
  11. 11.
    Goodwin WE, Scardino PL, Scott WW. Penile prosthesis for impotence: case report. J Urol. 1981;126(3):409.PubMedGoogle Scholar
  12. 12.
    Beheri GE. Surgical treatment of impotence. Plast Reconstr Surg. 1966;38(2):92–7.PubMedGoogle Scholar
  13. 13.
    Scott FB, Bradley WE, Timm GW. Management of erectile impotence. Use of implantable inflatable prosthesis. Urology. 1973;2(1):80–2.PubMedPubMedCentralGoogle Scholar
  14. 14.
    Small MP, Carrion HM, Gordon JA. Small-Carrion penile prosthesis. New implant for management of impotence. Urology. 1975;5(4):479–86.PubMedGoogle Scholar
  15. 15.
    Merrill DC. Mentor inflatable penile prosthesis: clinical experience in 52 patients. Br J Urol. 1984;56(5):512–5.PubMedGoogle Scholar
  16. 16.
    Merrill DC, Javaheri P. Mentor inflatable penile prosthesis. Preliminary clinical results in 30 patients. Urology. 1984;23(5):72–4.PubMedGoogle Scholar
  17. 17.
    Michal V, et al. Direct arterial anastomosis on corpora cavernosa penis in the therapy of erective impotence. Rozhl Chir. 1973;52(9):587–90.PubMedGoogle Scholar
  18. 18.
    Michal V, Pospichal J, Lachman M. Penile arterial occlusions in erection impotence. A new type of angiography-phalloarteriography. Cas Lek Cesk. 1976;115(40):1245–7.PubMedGoogle Scholar
  19. 19.
    Michal V, et al. Arterial epigastricocavernous anastomosis for the treatment of sexual impotence. World J Surg. 1977;1(4):515–9.PubMedGoogle Scholar
  20. 20.
    Dicks B, Bastuba M, Goldstein I. Penile revascularization--contemporary update. Asian J Androl. 2013;15(1):5–9.PubMedGoogle Scholar
  21. 21.
    Carson CC 3rd. Efficacy of antibiotic impregnation of inflatable penile prostheses in decreasing infection in original implants. J Urol. 2004;171(4):1611–4.PubMedPubMedCentralGoogle Scholar
  22. 22.
    Wolter CE, Hellstrom WJ. The hydrophilic-coated inflatable penile prosthesis: 1-year experience. J Sex Med. 2004;1(2):221–4.Google Scholar
  23. 23.
    Wilson SK, et al. The mentor Alpha 1 penile prosthesis with reservoir lock-out valve: effective prevention of auto-inflation with improved capability for ectopic reservoir placement. J Urol. 2002;168(4 Pt 1):1475–8.PubMedGoogle Scholar
  24. 24.
    Knoll LD, et al. Physician and patient satisfaction with the new AMS 700 momentary squeeze inflatable penile prosthesis. J Sex Med. 2009;6(6):1773–8.PubMedGoogle Scholar
  25. 25.
    Ulloa EW, Silberbogen AK, Brown K. Preoperative psychosocial evaluation of penile prosthesis candidates. Am J Mens Health. 2008;2(1):68–75.PubMedGoogle Scholar
  26. 26.
    Bettocchi C, et al. Penile prostheses. Ther Adv Urol. 2010;2(1):35–40.PubMedPubMedCentralGoogle Scholar
  27. 27.
    Kramer AC, Schweber A. Patient expectations prior to coloplast titan penile prosthesis implant predicts postoperative satisfaction. J Sex Med. 2010;7(6):2261–6.PubMedGoogle Scholar
  28. 28.
    Yeung LL, et al. A comparison of chlorhexidine-alcohol versus povidone-iodine for eliminating skin flora before genitourinary prosthetic surgery: a randomized controlled trial. J Urol. 2013;189(1):136–40.PubMedPubMedCentralGoogle Scholar
  29. 29.
    Eid JF, et al. Coated implants and “no touch” surgical technique decreases risk of infection in inflatable penile prosthesis implantation to 0.46%. Urology. 2012;79(6):1310–5.PubMedPubMedCentralGoogle Scholar
  30. 30.
    Sadeghi-Nejad H, et al. Multi-institutional outcome study on the efficacy of closed-suction drainage of the scrotum in three-piece inflatable penile prosthesis surgery. Int J Impot Res. 2005;17(6):535–8.PubMedPubMedCentralGoogle Scholar
  31. 31.
    Kramer A, Goldmark E, Greenfield J. Is a closed-suction drain advantageous for penile implant surgery? The debate continues. J Sex Med. 2011;8(2):601–6.PubMedGoogle Scholar
  32. 32.
    Wosnitzer MS, Greenfield JM. Antibiotic patterns with inflatable penile prosthesis insertion. J Sex Med. 2011;8(5):1521–8.PubMedPubMedCentralGoogle Scholar
  33. 33.
    Chung E, et al. Comparison between AMS 700 CX and Coloplast Titan inflatable penile prosthesis for Peyronie’s disease treatment and remodeling: clinical outcomes and patient satisfaction. J Sex Med. 2013;10(11):2855–60.Google Scholar
  34. 34.
    Morgado A, et al. Long-term patient-reported satisfaction with different inflatable penile prosthesis: comparison between AMS 700CX and Coloplast Titan. Rev Int Androl. 2018;16(3):112–8.PubMedGoogle Scholar
  35. 35.
    Akin-Olugbade O, et al. Determinants of patient satisfaction following penile prosthesis surgery. J Sex Med. 2006;3(4):743–8.PubMedGoogle Scholar
  36. 36.
    Miranda-Sousa A, et al. Concomitant ventral phalloplasty during penile implant surgery: a novel procedure that optimizes patient satisfaction and their perception of phallic length after penile implant surgery. J Sex Med. 2007;4(5):1494–9.PubMedGoogle Scholar
  37. 37.
    Henry G, et al. Comparison of a new length measurement technique for inflatable penile prosthesis implantation to standard techniques: outcomes and patient satisfaction. J Sex Med. 2011;8(9):2640–6.PubMedGoogle Scholar
  38. 38.
    Henry GD, Jennermann C, Eid JF. Evaluation of satisfaction and axial rigidity with titan XL cylinders. Adv Urol. 2012;2012:896070.PubMedPubMedCentralGoogle Scholar
  39. 39.
    Egydio PH, Kuehhas FE, Valenzuela RJ. Modified sliding technique (MoST) for penile lengthening with insertion of inflatable penile prosthesis. J Sex Med. 2015;12(5):1100–4.PubMedGoogle Scholar
  40. 40.
    Negro CL, et al. Implantation of AMS 700 LGX penile prosthesis preserves penile length without the need for penile lengthening procedures. Asian J Androl. 2016;18(1):114–7.PubMedGoogle Scholar
  41. 41.
    Shaeer O, et al. Dorsal phalloplasty accompanying penile prosthesis implantation minimizes penile shortening and improves patient satisfaction. Int J Impot Res. 2018;  https://doi.org/10.1038/s41443-018-0085-8.PubMedGoogle Scholar
  42. 42.
    Serefoglu EC, et al. Long-term revision rate due to infection in hydrophilic-coated inflatable penile prostheses: 11-year follow-up. J Sex Med. 2012;9(8):2182–6.PubMedPubMedCentralGoogle Scholar
  43. 43.
    Mandava SH, et al. Infection retardant coated inflatable penile prostheses decrease the incidence of infection: a systematic review and meta-analysis. J Urol. 2012;188(5):1855–60.PubMedPubMedCentralGoogle Scholar
  44. 44.
    Wilson SK, Costerton JW. Biofilm and penile prosthesis infections in the era of coated implants: a review. J Sex Med. 2012;9(1):44–53.Google Scholar
  45. 45.
    Gross MS, et al. Multicenter investigation of the micro-organisms involved in penile prosthesis infection: an analysis of the efficacy of the AUA and EAU guidelines for penile prosthesis prophylaxis. J Sex Med. 2017;14(3):455–63.PubMedPubMedCentralGoogle Scholar
  46. 46.
    Henry GD, et al. An outcomes analysis of over 200 revision surgeries for penile prosthesis implantation: a multicenter study. J Sex Med. 2012;9(1):309–15.PubMedPubMedCentralGoogle Scholar
  47. 47.
    Mulcahy JJ. Long-term experience with salvage of infected penile implants. J Urol. 2000;163(2):481–2.PubMedPubMedCentralGoogle Scholar
  48. 48.
    Gross MS, et al. The malleable implant salvage technique: infection outcomes after Mulcahy salvage procedure and replacement of infected inflatable penile prosthesis with malleable prosthesis. J Urol. 2016;195(3):694–7.PubMedPubMedCentralGoogle Scholar
  49. 49.
    Mulcahy JJ, Wilson SK. Current use of penile implants in erectile dysfunction. Curr Urol Rep. 2006;7(6):485–9.PubMedGoogle Scholar
  50. 50.
    Mulcahy JJ. Current approach to the treatment of penile implant infections. Ther Adv Urol. 2010;2(2):69–75.PubMedPubMedCentralGoogle Scholar
  51. 51.
    Wilson SK, et al. Long-term survival of inflatable penile prostheses: single surgical group experience with 2,384 first-time implants spanning two decades. J Sex Med. 2007;4(4 Pt 1):1074–9.Google Scholar
  52. 52.
    Hinds PR, Wilson SK, Sadeghi-Nejad H. Dilemmas of inflatable penile prosthesis revision surgery: what practices achieve the best outcomes and the lowest infection rates? (CME). J Sex Med. 2012;9(10):2483–91; quiz 2492.PubMedGoogle Scholar
  53. 53.
    Levine LA, Hoeh MP. Review of penile prosthetic reservoir: complications and presentation of a modified reservoir placement technique. J Sex Med. 2012;9(11):2759–69.PubMedGoogle Scholar
  54. 54.
    Kaufman JM, Weldon TE. Cylinder aneurysm of parylene-coated American Medical System (AMS) 700CX penile prosthesis. J Sex Med. 2008;5(11):2713–5.PubMedGoogle Scholar
  55. 55.
    Talib RA, et al. Isolated pump erosion of an inflatable penile prosthesis through the scrotum in a diabetic patient. Arch Ital Urol Androl. 2013;85(1):53–5.PubMedGoogle Scholar
  56. 56.
    Leach GE, et al. Erosion of inflatable penile prosthesis reservoir into bladder and bowel. J Urol. 1984;131(6):1177–8.PubMedGoogle Scholar
  57. 57.
    Fitch WP 3rd, Roddy T. Erosion of inflatable penile prosthesis reservoir into bladder. J Urol. 1986;136(5):1080.PubMedGoogle Scholar
  58. 58.
    Godiwalla SY, Beres J, Jacobs SC. Erosion of an inflatable penile prosthesis reservoir into an ileal conduit. J Urol. 1987;137(2):297–8.PubMedGoogle Scholar
  59. 59.
    Dupont MC, Hochman HI. Erosion of an inflatable penile prosthesis reservoir into the bladder, presenting as bladder calculi. J Urol. 1988;139(2):367–8.PubMedGoogle Scholar
  60. 60.
    Tran CN, et al. Erosion of inflatable penile prosthesis reservoir into neobladder. J Sex Med. 2013;10(9):2343–6.PubMedGoogle Scholar
  61. 61.
    Wilson SK, Cleves MA, Delk JR 2nd. Ultrex cylinders: problems with uncontrolled lengthening (the S-shaped deformity). J Urol. 1996;155(1):135–7.PubMedGoogle Scholar
  62. 62.
    Moncada I, et al. Buckling of cylinders may cause prolonged penile pain after prosthesis implantation: a case control study using magnetic resonance imaging of the penis. J Urol. 1998;160(1):67–71.PubMedGoogle Scholar
  63. 63.
    Mulhall JP, Kim FJ. Reconstructing penile supersonic transporter (SST) deformity using glanulopexy (glans fixation). Urology. 2001;57(6):1160–2.PubMedGoogle Scholar
  64. 64.
    Ziegelmann MJ, et al. Modified Glanulopexy technique for supersonic transporter deformity and glanular hypermobility in men with penile prostheses. J Sex Med. 2018;15(6):914–9.PubMedPubMedCentralGoogle Scholar
  65. 65.
    Carson CC, Mulcahy JJ, Govier FE. Efficacy, safety and patient satisfaction outcomes of the AMS 700CX inflatable penile prosthesis: results of a long-term multicenter study. AMS 700CX Study Group. J Urol. 2000;164(2):376–80.PubMedGoogle Scholar
  66. 66.
    Abbosh PH, Thom MR, Bullock A. Laparascopic capsulotomy to treat autoinflation of inflatable penile prostheses. J Sex Med. 2012;9(4):1212–5.PubMedGoogle Scholar
  67. 67.
    Wilson SK, et al. Glans necrosis following penile prosthesis implantation: prevention and treatment suggestions. Urology. 2017;107:144–8.PubMedGoogle Scholar
  68. 68.
    Rao DS, Donatucci CF. Vasculogenic impotence. Arterial and venous surgery. Urol Clin North Am. 2001;28(2):309–19.PubMedGoogle Scholar
  69. 69.
    Goldstein I, et al. Penile revascularization. J Sex Med. 2008;5(9):2018–21.PubMedGoogle Scholar
  70. 70.
    Bertero EB, Antunes DL. Surgical treatment of erectile dysfunction. Sex Med Rev. 2015;3(4):316–27.PubMedGoogle Scholar
  71. 71.
    Trost LW, et al. External mechanical devices and vascular surgery for erectile dysfunction. J Sex Med. 2016;13(11):1579–617.PubMedGoogle Scholar
  72. 72.
    Sohn M, et al. Standard operating procedures for vascular surgery in erectile dysfunction: revascularization and venous procedures. J Sex Med. 2013;10(1):172–9.PubMedGoogle Scholar
  73. 73.
    Kim ED, et al. Endovascular treatment of vasculogenic erectile dysfunction. Asian J Androl. 2015;17(1):40–3.PubMedGoogle Scholar
  74. 74.
    Dabaja AA, Teloken P, Mulhall JP. A critical analysis of candidacy for penile revascularization. J Sex Med. 2014;11(9):2327–32.PubMedGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Afonso Morgado
    • 1
    • 2
  • Nuno Tomada
    • 3
  • Joaquim Sarquella
    • 4
  1. 1.Serviço de Urologia, Centro Hospitalar Universitário São JoãoPortoPortugal
  2. 2.Departamento de BiomedicinaFaculdade de Medicina da Universidade do PortoPortoPortugal
  3. 3.Nuno Tomada Urologia e Cirurgia ReconstrutivaPortoPortugal
  4. 4.Andrology DepartmentFundació PuigvertBarcelonaSpain

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