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Recurrent Febrile Episodes and Abdominal Pain

  • Per WekellEmail author
  • Stefan Berg
  • Anders Fasth
Chapter

Abstract

Familial Mediterranean fever (FMF) should be suspected in children with recurrent, fever attacks of short duration, 6 hours-3 days, associated with peritonitis, pleuritis and/or arthritis

FMF is most common in populations with eastern Mediterranean origin

FMF is considered an autosomal recessive disease, yet biallelic mutations are not always identified

Colchicine is the drug-of-choice that effectively prevents FMF attacks and amyloidosis

Secondary amyloidosis is the main long-term complication in untreated patients

Keywords

Familial Mediterranean fever Colchicine MEFV 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Pediatrics, NU Hospital GroupUddevallaSweden
  2. 2.Department of Pediatrics, Sahlgrenska Academy, University of GothenburgGothenburgSweden
  3. 3.Department of Rheumatology and Immunology, Queen Silvia Children’s HospitalGothenburgSweden

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