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Recurrent Invasive Bacterial Infections

  • Anna Hilfanova
  • Dariia Osypchuk
  • Anastasiia Bondarenko
Chapter

Abstract

  • Fungal infections, such as with Aspergillus spp., should always be considered in this patient group if they do not respond as expected to empirical antibiotic therapy

  • X-linked chronic granulomatous disease (CGD) is caused by mutations in the CYBB gene responsible to encode the p91phox of the NADPH oxidase complex

  • BCG vaccine is contraindicated in CGD

  • Organisms like Burkholderia cepacia and Klebsiella, Serratia found in water reservoirs are not virulent for normal swimmers but may be infectious for CGD patients

Keywords

Nitroblue tetrazolium Aspergillus fumigatus Burkholderia cepacia Klebsiella Serratia Chronic granulomatous disease 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Anna Hilfanova
    • 1
  • Dariia Osypchuk
    • 2
  • Anastasiia Bondarenko
    • 1
  1. 1.Shupyk National Medical Academy for Postgraduate Education, Department of Pediatric Infectious Diseases and Pediatric ImmunologyKyivUkraine
  2. 2.Institute of Pediatrics, Obstetrics and Gynecology, Laboratory of ImmunologyKyivUkraine

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