Delayed Umbilical Cord Separation

  • Alireza Shafiei


Delayed umbilical cord separation, recurrent mucocutaneous infections and pleocytosis the most possible diagnosis is leukocyte adhesion deficiency (LAD)

The diagnosis of LAD type 1 is established by flow cytometric measurements of CD18 on lymphocytes


Leukocyte adhesion deficiency CD18 Delayed umbilical cord separation 


  1. 1.
    Etzioni A. Defects in the leukocyte adhesion cascade. Clin Rev Allergy Immunol. 2010;38(1):54–60.CrossRefGoogle Scholar
  2. 2.
    Madkaikar M, Currimbhoy Z, Gupta M, Desai M, Rao M. Clinical profile of leukocyte adhesion deficiency type I. Indian Pediatr. 2012;49(1):43–5.CrossRefGoogle Scholar

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Alireza Shafiei
    • 1
  1. 1.Department of Allergy and Clinical ImmunologyBahrami Hospital, School of Medicine, Tehran University of Medical SciencesTehranIran

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