Chronic Papulovegetative Ulcer on Penis

  • Mahboubeh Mansouri


  • DOCK8 deficiency is a combined immunodeficiency commonly presenting with severe viral infections of skin

  • Cutaneous viral infections with HPV, HSV and CMV viruses are common in autosomal recessive hyper IgE syndrome


Cytomegalovirus Herpes simplex virus Human papilloma virus Hyper IgE syndrome 


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    Biggs CM, Keles S, Chatila TA. DOCK8 deficiency: insights into pathophysiology, clinical features and management. Clin Immunol. 2017;181:75–82.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Mahboubeh Mansouri
    • 1
  1. 1.Department of Immunology and AllergyMofid Children’s Hospital, Shahid Beheshti University of Medical SciencesTehranIran

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