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Gingivitis and Recurrent Tonsillitis

  • Suzan Çınar
  • Manolya Kara
  • Gunnur Deniz
Chapter

Abstract

Family history of a patient with hyper-IgM syndrome is a cornerstone of the diagnosis

Serum IgA, IgM and IgE levels might be normal, but serum IgG level is always reduced with high to normal number of B cells

Acquired forms of hyper-IgM can be seen in congenital rubella syndrome, use of antiepileptic drugs like phenytoin, and malignancies such as T cell leukemia, multiple myeloma, and lymphoma

Keywords

Hyper IgM syndrome Congenital rubella syndrome CD40L Cholangiocarcinoma 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Suzan Çınar
    • 1
  • Manolya Kara
    • 2
  • Gunnur Deniz
    • 1
  1. 1.Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of ImmunologyFatih/IstanbulTurkey
  2. 2.Istanbul University, Istanbul Medical Faculty, Department of Pediatrics, Pediatric Infectious Diseases and Clinical ImmunologyFatih/İstanbulTurkey

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