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BCGosis and Hyperferritinemia

  • Neslihan Edeer Karaca
  • Guzide Aksu
  • Necil Kutukculer
Chapter

Abstract

  • Mycobacterial infections, particularly with low-virulence mycobacteria, may point toward a defect in the type 1 cytokine pathway or the IL-12:IFN-γ loop

  • Patients with NEMO defect may present without ectodermal dysplasia

  • NEMO mutations should be considered in all males with disseminated mycobacterial infection

  • High ferritin levels, which is a marker of systemic inflammation, may accompany active mycobacterial disease

Keywords

Mendelian susceptibility to mycobacterial disease IL-12:IFN-γ NEMO Ectodermal dysplasia 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Neslihan Edeer Karaca
    • 1
  • Guzide Aksu
    • 1
  • Necil Kutukculer
    • 1
  1. 1.Ege University Faculty of Medicine, Department of Pediatric ImmunologyIzmirTurkey

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