Cough and Dyspnea

  • Javad Ghaffari


  • Increased serum IgE concentrations, usually above 2000 IU/mL, and eosinophil levels above 90%, are present in both forms of the hyper IgE syndrome (HIES)

  • Coarse facial features, short stature, early osteoporosis, frequent fractures, scoliosis, mucocutaneous candidiasis in form of thrush, vaginal candidiasis or candida nail infection, craniosynostosis, hyper flexible joints, delay shedding of primary teeth are in favour of autosomal dominant form of HIES


Hyper IgE syndrome Craniosynostosis hypeflexibility Scoliosis 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Javad Ghaffari
    • 1
  1. 1.Mazandaran University of Medical SciencesSariIran

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