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Thrombocytopenia

  • Anna Fahy Hagan
  • Scott HaganEmail author
Chapter
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Abstract

Thrombocytopenia is a common hematologic abnormality encountered during perioperative testing. Severe thrombocytopenia and platelet dysfunction may increase the bleeding risk of surgery. Identifying thrombocytopenia and determining the etiology in the perioperative period are important to reduce the risk of surgical complications.

Keywords

Thrombocytopenia Bleeding Transfusion Platelets Platelet dysfunction Immune thrombocytopenia Preoperative Perioperative 
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References

  1. 1.
    Gauer RL, Braun MM. Thrombocytopenia. Am Fam Physician. 2012;85(6):612–22.PubMedGoogle Scholar
  2. 2.
    Feely MA, et al. Preoperative testing before noncardiac surgery: guidelines and recommendations. Am Fam Physician. 2013;87(6):414–8.Google Scholar
  3. 3.
    American Society of Anesthesiologists Task Force on Perioperative Blood Management. Practice guidelines for perioperative blood management: an updated report by the American Society of Anesthesiologists Task Force on perioperative blood management. Anesthesiology. 2015;122(2):241–75.CrossRefGoogle Scholar
  4. 4.
    Kaufman RM, Djulbegovic B, Gernsheimer T, et al. Platelet transfusion: a clinical practice guideline from the AABB. Ann Intern Med. 2015;162(3):205–13. Open image in new windowGoogle Scholar
  5. 5.
    Mccullough J. Overview of platelet transfusion. Semin Hematol. 2010;47(3):235–42.CrossRefGoogle Scholar
  6. 6.
    Mannucci PM, Remuzzi G, Pusineri F, et al. Deamino-8-D-arginine vasopressin shortens the bleeding time in uremia. N Engl J Med. 1983;308(1):8–12.CrossRefGoogle Scholar
  7. 7.
    Liumbruno GM, Bennardello F, Lattanzio A, et al. Recommendations for the transfusion management of patients in the peri-operative period. I. the pre-operative period. Blood Transfus. 2011;9(1):19–40.PubMedPubMedCentralGoogle Scholar
  8. 8.
    Mannucci PM, Tripodi A. Hemostatic defects in liver and renal dysfunction. Hematology Am Soc Hematol Educ Program. 2012;2012:168–73.CrossRefGoogle Scholar
  9. 9.
    Palevsky PM. Perioperative management of patients with chronic kidney disease or ESRD. Best Pract Res Clin Anaesthesiol. 2004;18(1):129–44.CrossRefGoogle Scholar
  10. 10.
    Lakshmanan S, Cuker A. Contemporary management of primary immune thrombocytopenia in adults. J Thromb Haemost. 2012;10(10):1988–98.CrossRefGoogle Scholar
  11. 11.
    Neunert C, Lim W, Crowther M, Cohen A, Solberg L Jr, Crowther MA. The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood. 2011;117(16):4190–207.CrossRefGoogle Scholar
  12. 12.
    Mithoowani S, Gregory-Miller K, Goy J, et al. High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis. Lancet Haematol. 2016;3(10):e489.CrossRefGoogle Scholar
  13. 13.
    Chang JC. Review: postoperative thrombocytopenia: with etiologic, diagnostic, and therapeutic consideration. Am J Med Sci. 1996;311(2):96–105. Open image in new windowGoogle Scholar
  14. 14.
    Cuker A, Gimotty PA, Crowther MA, Warkentin TE. Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis. Blood. 2012;120(20):4160–7.CrossRefGoogle Scholar

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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Medicine, Division of General Internal MedicineUniversity of WashingtonSeattleUSA

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