Advertisement

Multiple Blisters Over the Dorsum of the Hand

  • Wojciech BaranEmail author
  • Jacek Szepietowski
Chapter

Practical Points

  • Allergic contact dermatitis is caused by type IV delayed hypersensitivity reaction

  • In the induction phase, contact allergens cross the horny layer of the epidermis and form hapten-protein conjugates, which are presented to T cells by Langerhans cells

  • Activated T cells evolve into dermal memory T cells and trigger acute immune system reaction after next exposure to the allergen, in the elicitation phas

Keywords

Allergic contact dermatitis Temporary black henna tattoo Delayed-type hypersensitivity reaction 

References

  1. 1.
    Kaplan DH. Early events in the induction of allergic contact dermatitis. Nat Rev Immunol. 2012;12(2):114–24.CrossRefGoogle Scholar
  2. 2.
    Spornraft-Ragaller P, Schnuch A, Uter W. Extreme patch test reactivity to p-phenylenediamine but not to other allergens in children. Contact dermat. 2011;65(4):220–6.CrossRefGoogle Scholar
  3. 3.
    Panfili E, Esposito S, Di Cara G. Temporary Black Henna Tattoos and Sensitization to para-Phenylenediamine (PPD): two paediatric case reports and a review of the literature. Int J Environ Res Public Health. 2017;14(4):pii:E421.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Dermatology, Venereology and AllergologyWroclaw Medical UniversityWroclawPoland

Personalised recommendations