Advertisement

Abdominal Rash and a History of Hirschsprung

  • Mahboubeh MansouriEmail author
Chapter

Practical Points

  • In contrast to IgE-mediated clinical reaction in food allergy the clinical presentations in Eosinophilic associated gastrointestinal disorders (EGID) are not straight forward and might be misleading

  • Clinical symptoms are variable according to the site and layer of infiltration of eosinophils in esophagus, stomach, duodenum or colon or location of eosinophil infiltration in submucosal, muscular or subserosal layers

  • The diagnosis of EGID needs a high index of suspicion by the physician

  • The diagnosis of EGID should be considered in the presence of any chronic symptoms in the GI tract, with or without atopic diathesis

  • Multiple biopsies depending on site of the involvement, must be taken, in spite of normal look mucosa

Keywords

Eosinophilic gastrointestinal disorders Protein loosing enteropathy Elimination diet 

References

  1. 1.
    Mansoor E, Saleh MA, Cooper GS. Prevalence of eosinophilic gastroenteritis and colitis in a population-based study, from 2012 to 2017. Clin Gastroenterol Hepatol. 2017;15(11):1733–41.CrossRefGoogle Scholar
  2. 2.
    Tien FM, Wu JF, Jeng YM, Hsu HY, Ni YH, Chang MH, Lin DT, Chen HL. Clinical features and treatment responses of children with eosinophilic gastroenteritis. Pediatr Neonatol. 2011;52(5):272–8.CrossRefGoogle Scholar
  3. 3.
    Schoepfer A. Diagnostic approach to eosinophilic oesophagitis: pearls and pitfalls. Best Pract Res Clin Gastroenterol. 2015;29(5):783–92.CrossRefGoogle Scholar
  4. 4.
    Leung J, Beukema KR, Shen AH. Allergic mechanisms of Eosinophilic oesophagitis. Best Pract Res Clin Gastroenterol. 2015;29(5):709–20.CrossRefGoogle Scholar
  5. 5.
    Wang F, Han J. Delayed eosinophilic gastroenteritis, a possible side effect of clopidogrel? Int J Cardiol. 2013;165(3):e53–4.CrossRefGoogle Scholar
  6. 6.
    Yamada Y, Kato M, Isoda Y, Nishi A, Jinbo Y, Hayashi Y. Eosinophilic gastroenteritis treated with a multiple-food elimination diet. Allergol Int. 2014;63(Suppl 1):53–6.CrossRefGoogle Scholar
  7. 7.
    Siewert E, Lammert F, Koppitz P, Schmidt T, Matern S. Eosinophilic gastroenteritis with severe protein-losing enteropathy: successful treatment with budesonide. Dig Liver Dis. 2006;38(1):55–9.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Immunology and Allergy, Mofid Children’s HospitalShahid Beheshti University of Medical SciencesTehranIran

Personalised recommendations