Advertisement

Acute Reaction After Drinking Formula Milk

  • Kok Wee Chong
  • Wenyin Loh
  • Jan Hau LeeEmail author
Chapter

Practical Points

  • Cow’s milk and egg allergy are the most common causes of food allergy in children

  • Most patients develop natural tolerance by first year of age

  • Acute onset of symptoms such as urticaria, angioedema, nausea, vomiting, wheezing following food ingestion, should prompt a diagnosis of food allergy

  • Allergy to galacto-oligosaccharides, a prebiotic carbohydrate, has been recently described in atopic patients in South-East Asia

  • Galacto-oligosaccharides allergy is contrary to conventional understanding that allergens are proteins or glycoproteins

Keywords

Diphenhydramine Galacto-oligosaccharides Antihistamine Food allergy 

References

  1. 1.
    Sánchez-Borges M, Suárez-Chacon R, Capriles-Hulett A, Caballero-Fonseca F, Iraola V, Fernández-Caldas E. Pancake syndrome (oral mite anaphylaxis). World Allergy Organ J. 2009;2(5):91–6.CrossRefGoogle Scholar
  2. 2.
    Chiang WC, Huang CH, Llanora GV, Gerez I, Goh SH, Shek LP, Nauta AJ, Van Doorn WA, Bindels J, Ulfman LH, Knipping K, Delsing DJ, Knol EF, Lee BW. Anaphylaxis to cow’s milk formula containing short-chain galacto-oligosaccharide. J Allergy Clin Immunol. 2012;130(6):1361–7.CrossRefGoogle Scholar
  3. 3.
    Soh JY, Huang CH, Chiang WC, Llanora GV, Lee AJ, Loh W, Chin YL, Tay VY, Chan YH, Dianne D, Lee BW. Anaphylaxis to galacto-oligosaccharides--an evaluation in an atopic population in Singapore. Allergy. 2015;70(8):1020–3.CrossRefGoogle Scholar
  4. 4.
    Kaneko K, Watanabe Y, Kimura K, Matsumoto K, Mizobuchi T, Onoue M. Development of hypoallergenic galacto-oligosaccharides on the basis of allergen analysis. Biosci Biotechnol Biochem. 2014;78(1):100–8.CrossRefGoogle Scholar
  5. 5.
    Muraro A, Roberts G, Worm M, Bilo MB, Brockow K, Fernandez Rivas M, Santos AF, Zolkipli ZQ, Bellou A, Beyer K, Bindslev-Jensen C, Cardona V, Clark AT, Demoly P, Dubois AE, DunnGalvin A, Eigenmann P, Halken S, Harada L, Lack G, Jutel M, Niggemann B, Rueff F, Timmermans F, Vlieg-Boerstra BJ, Werfel T, Dhami S, Panesar S, Akdis CA, Sheikh A. Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology. Allergy. 2014;69(8):1026–45.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Allergy Service, Department of Paediatric MedicineKK Women’s and Children’s HospitalSingaporeSingapore
  2. 2.Children’s Intensive Care UnitKK Women’s and Children’s HospitalSingaporeSingapore

Personalised recommendations