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The Practical Consequences of Observed Associations Between Maternal Use of Drugs and Infant Congenital Malformations

  • Bengt Källén
Chapter

Abstract

This chapter discusses how epidemiological data which more or less certainly demonstrate a risk should affect drug use in practice. The difference is stressed between the situation where a definite teratogenicity is known and that when a new finding has appeared in a study, suspecting an association between maternal drug use and infant malformations. The effects of mass significance and confounding by indication are pointed out. The practical consequences of identified probable causal associations are discussed.

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Bengt Källén
    • 1
  1. 1.Tornblad Institute for Comparative EmbryologyLund UniversityLundSweden

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