Characterizing Parkinson’s Disease from Speech Samples Using Deep Structured Learning

  • Lígia SousaEmail author
  • Diogo Braga
  • Ana Madureira
  • Luis Coelho
  • Francesco Renna
Conference paper
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 942)


An early detection of neurodegenerative diseases, such as Parkinson’s disease, can improve therapy effectiveness and, by consequence, the patient’s quality of life. This paper proposes a new methodology for automatic classification of voice samples regarding the presence of acoustic patterns of Parkinson’s disease, using a deep structured neural network. This is a low cost non-invasive approach that can raise alerts in a pre-clinical stage. Aiming to a higher diagnostic detail, it is also an objective to accurately estimate the stage of evolution of the disease allowing to understand in what extent the symptoms have developed. Therefore, two types of classification problems are explored: binary classification and multiclass classification. For binary classification, a deep structured neural network was developed, capable of correctly diagnosing 93.4% of cases. For the multiclass classification scenario, in addition to the deep neural network, a K-nearest neighbour algorithm was also used to establish a reference for comparison purposes, while using a common database. In both cases the original feature set was optimized using principal component analysis and the results showed that the proposed deep structure neural network was able to provide more accurate estimations about the disease’s stage, reaching a score of 84.7%. The obtained results are promising and create the motivation to further explore the model’s flexibility and to pursue better results.


Voice analysis Parkinson’s disease Deep neural networks 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Lígia Sousa
    • 1
    Email author
  • Diogo Braga
    • 2
    • 4
  • Ana Madureira
    • 2
    • 4
  • Luis Coelho
    • 2
    • 3
  • Francesco Renna
    • 5
  1. 1.Faculdade de Medicina da Universidade do PortoPortoPortugal
  2. 2.ISEP/IPPPortoPortugal
  3. 3.CIETI - Centro de Inovação em Engenharia e Tecnologia IndustrialPortoPortugal
  4. 4.ISRC - Interdisciplinary Studies Research CenterPortoPortugal
  5. 5.Instituto de TelecomunicaçõesFaculdade de Ciências da Universidade do PortoPortoPortugal

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