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Hand Function in Scleroderma

  • Cosimo Bruni
  • Angela Del Rosso
  • Marco Matucci Cerinic
  • Susanna Maddali Bongi
Chapter

Abstract

Systemic sclerosis or scleroderma (SSc) is characterized by immunologic abnormalities, microvascular alterations, and excessive collagen production, leading to fibrosis of skin and internal organs (lungs, heart, gastrointestinal tract).

Hands are prominent targets of SSc and may be involved at different levels. Frequent signs and symptoms of the disease, such as skin and microcirculatory impairment as well as musculoskeletal involvement (of joints, tendons, and muscles), usually begin from the hands. Hand involvement evolves throughout all the course of the disease and leads to important disability in SSc.

This chapter will analyze the involvement of the hands in SSc, focusing on the causes and the kind of functional disturbances, the relation between hand impairment and other clinical parameters, hand function in different stages of the disease, and the tools to assess damage and function of the hand.

Keywords

Systemic sclerosis Disability Handicap Quality of life Hand Fingers Scleroderma Claw type deformities Raynaud phenomenon Digital ulcers Arthritis Duruoz Hand Index (DHI) UK scleroderma functional score (UKFS) Hand Mobility in Scleroderma (HAMIS) test 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Cosimo Bruni
    • 1
    • 2
  • Angela Del Rosso
    • 1
    • 2
  • Marco Matucci Cerinic
    • 1
    • 2
  • Susanna Maddali Bongi
    • 1
    • 2
  1. 1.Department of Experimental and Clinical MedicineUniversity of FlorenceFlorenceItaly
  2. 2.Division of RheumatologyAzienda Ospedaliera Universitaria CareggiFlorenceItaly

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