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Bioluminescence Technology to Aid Lesion Activity Assessment

  • Christopher LongbottomEmail author
  • Bruce Vernon
Chapter

Abstract

Calcivis Imaging System is a novel device that detects the presence of free calcium ions as an indication of active enamel demineralization. The system uses a photoprotein that interacts with free calcium ions eliciting a bioluminescence signal. Using a specialized software, the system captures the bioluminescence image. Studies have indicated a direct correlation between intensity of luminescence and calcium concentration. Ongoing studies will further elucidate the value of this system in caries activity assessment and management.

Keywords

Caries Lesion activity Lesion assessment Luminescence Bioluminescence Imaging 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.King’s College London Dental InstituteLondonUK
  2. 2.Calcivis Ltd.EdinburghUK

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