Bioluminescence Technology to Aid Lesion Activity Assessment
Calcivis Imaging System is a novel device that detects the presence of free calcium ions as an indication of active enamel demineralization. The system uses a photoprotein that interacts with free calcium ions eliciting a bioluminescence signal. Using a specialized software, the system captures the bioluminescence image. Studies have indicated a direct correlation between intensity of luminescence and calcium concentration. Ongoing studies will further elucidate the value of this system in caries activity assessment and management.