CyberKnife Robotic Stereotactic Radiosurgery

  • Erqi Pollom
  • Lei Wang
  • Iris C. Gibbs
  • Scott G. SoltysEmail author


The CyberKnife, developed by John Adler, a neurosurgeon at Stanford, treated its first patient in 1994. This pioneering system was the first dedicated stereotactic radiosurgery device that did not require an invasive stereotactic frame, allowing investigation of stereotactic principles in extracranial sites. The CyberKnife led to early studies of stereotactic radiotherapy for the lung, pancreas, spine, prostate, and other sites in the body. We review the early history of the development of the CyberKnife, describe the components of the system that allow for stereotactic accuracy, highlight how advances in the technology over the years have contributed to clinical outcomes, and look to where the CyberKnife, and the field of radiosurgery, may be headed in the future.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Erqi Pollom
    • 1
    • 2
  • Lei Wang
    • 1
    • 2
  • Iris C. Gibbs
    • 1
    • 2
  • Scott G. Soltys
    • 1
    • 2
    Email author
  1. 1.Stanford Cancer InstituteStanfordUSA
  2. 2.Stanford University, Department of Radiation OncologyStanfordUSA

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