Paget’s disease of the breast is a rare breast tumor that was first identified by Sir James Paget in 1874. Paget’s disease of the breast is characterized by eczema-form changes accompanied by erosion and ulceration of the nipple and areolar epidermis and is mostly correlated with ductal carcinoma in situ (DCIS). Additionally, Paget’s disease of the breast can be accompanied by invasive ductal carcinoma (IDC). The diagnosis of Paget’s disease of the breast is determined upon microscopically observing Paget cells in a skin biopsy. The width of the lesion is evaluated via mammography and magnetic resonance imaging (MRI) in patients for whom breast-preserving surgery is planned. Depending on the extent of the lesion, sentinel lymph node biopsy and axillary curettage for those with axillary metastases are the treatment alternatives to breast-preserving surgery or mastectomy.
KeywordsPaget carcinoma Ulceration of the nipple Eczematous lesions Central resection
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