Age: A Criterion to Offer Surgical Treatment as a Cytoreductive Tool for Malignant Primary Brain Tumour?

  • Joseph H. McAbeeEmail author
  • Aida K. Golahmadi
  • Colin Watts


Elderly glioblastoma patients are often not considered for gross total resection, the validated optimal surgical treatment, due to concern about preoperative comorbidities or potential postoperative complications. However, recent studies suggest that cytoreductive surgery can be well tolerated and improve quality of life, progression free survival, and overall survival in the elderly population. Therefore, neurosurgeons must consider more holistic metrics, such as comprehensive geriatric assessments, when making operative decisions and should make a more concerted effort to include elderly patients in clinical trials.


Malignant brain tumour Age Surgery 

Supplementary material

438026_1_En_4_MOESM1_ESM.docx (227 kb)
Table 1 List of articles used for analysis (DOCX 26 kb)


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Joseph H. McAbee
    • 1
    Email author
  • Aida K. Golahmadi
    • 2
  • Colin Watts
    • 3
  1. 1.Department of Clinical Neurosciences, Cambridge Centre for Brain RepairUniversity of CambridgeCambridgeUK
  2. 2.School of Medicine, Imperial College London and Imperial College NHS TrustLondonUK
  3. 3.Birmingham Brain Cancer ProgramInstitute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of BirminghamBirminghamUK

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