Acute Lung Injury

  • Venerino Poletti
  • Giovanni Poletti
  • Christian Gurioli
  • Carlo Gurioli
  • Alessandra Dubini


Acute lung injury is a term that may be used to include patients with rapidly progressive respiratory failure and diffuse lung infiltrates. A variety of causes or clinical settings may be linked to this context. CT scan features and laboratory tests are helpful to significantly shorten the differential diagnostic list. Bronchoalveolar lavage (BAL) has an important diagnostic role because some causative agents may be identified by this approach, and also the cytological profile may greatly contribute to the definite diagnosis. In only a minority of patients, biopsy remains useful for planning treatment strategies. Whereas anecdotic reports and a few short series already addressed the role of regular transbronchial lung biopsy and surgical lung biopsy, the role of transbronchial cryobiopsy remains to be elucidated.


Acute respiratory distress syndrome Acute lung injury Pulmonary capillaritis Idiopathic interstitial pneumonia with autoimmune features Bronchoalveolar lavage Transbronchial lung cryobiopsy Diagnosis 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Venerino Poletti
    • 1
    • 2
  • Giovanni Poletti
    • 3
  • Christian Gurioli
    • 1
  • Carlo Gurioli
    • 1
  • Alessandra Dubini
    • 4
  1. 1.Department of Diseases of the ThoraxOspedale Morgagni-PierantoniForlìItaly
  2. 2.Department of Respiratory Diseases and AllergyAarhus University HospitalAarhusDenmark
  3. 3.Hematologic Section, CorelabAzienda USL Romagna, PievesestinaCesenaItaly
  4. 4.Department of Diseases of the Thorax-Pulmonology UnitAzienda Usl della Romagna, Ospedale GB MorgagniForlìItaly

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