Acute Lung Injury
Acute lung injury is a term that may be used to include patients with rapidly progressive respiratory failure and diffuse lung infiltrates. A variety of causes or clinical settings may be linked to this context. CT scan features and laboratory tests are helpful to significantly shorten the differential diagnostic list. Bronchoalveolar lavage (BAL) has an important diagnostic role because some causative agents may be identified by this approach, and also the cytological profile may greatly contribute to the definite diagnosis. In only a minority of patients, biopsy remains useful for planning treatment strategies. Whereas anecdotic reports and a few short series already addressed the role of regular transbronchial lung biopsy and surgical lung biopsy, the role of transbronchial cryobiopsy remains to be elucidated.
KeywordsAcute respiratory distress syndrome Acute lung injury Pulmonary capillaritis Idiopathic interstitial pneumonia with autoimmune features Bronchoalveolar lavage Transbronchial lung cryobiopsy Diagnosis
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