Diagnosing Abnormal Uterine Bleeding: The Standard of Care Has Changed

  • Ashraf Khafaga
  • Steven R. GoldsteinEmail author
Part of the ISGE Series book series (ISGE)


Abnormal uterine bleeding is a common presenting medical problem encountered in women in the gynecologic as well as the primary care setting. It has an overwhelming impact on these women’s quality of life and the utilization of the healthcare services. The annual prevalence rate of abnormal uterine bleeding in women ages 18–50 years was estimated as 53 per 1000 women. The availability of newer diagnostic tools has made it possible to promptly diagnose and treat an increasing number of such abnormal uterine bleeding in an office setting. Once a proper diagnosis has been established, appropriate therapy may be embarked upon. This chapter reviews the changes in the standard of care of patients presenting with abnormal uterine bleeding, in terms of the descriptive terms and diagnosis approach. In 2012, all those changes have been endorsed and enforced by the American Congress of Obstetrics and Gynecology, but unfortunately not all clinicians seem to be aware of that.


Abnormal uterine bleeding Postmenopause Perimenopause Blind biopsy Transvaginal ultrasonography Sonohysterography (SIS) PALM-COEIN system 


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Copyright information

© International Society of Gynecological Endocrinology 2019

Authors and Affiliations

  1. 1.Icahn School of Medicine at Mount SinaiNew YorkUSA
  2. 2.New York University School of MedicineNew YorkUSA

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