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Transcranial Direct Current Stimulation

  • Anna AmbrosiniEmail author
  • Gianluca Coppola
Chapter
Part of the Headache book series (HEAD)

Abstract

Migraine is the most prevalent neurological disorder worldwide; nevertheless, its pathophysiology is not yet completely understood. Recent scientific progresses in migraine research disclosed new possible targets for novel non-pharmacological treatment strategies for migraine treatment, such as noninvasive neuromodulation methods. Among them, transcranial direct current stimulation (tDCS) gave promising results in pilot studies. tDCS is a noninvasive, safe, and relatively not expensive technique of cortical electrical stimulation, aimed to modulate cortical activity in many ways, according to the stimulated sites and the polarity used. Unfortunately, large sham-controlled trials are not yet available to confirm its potential use as a preventative treatment for migraine.

Keywords

Migraine pathophysiology Preventative treatments Cortical neuromodulation Transcranial direct current stimulation tDCS 

Abbreviations

DLPFC

Dorsolateral prefrontal cortex

EEG

Electroencephalography

M1

Motor cortex

tDCS

Transcranial direct current stimulation

TMS

Transcranial magnetic stimulation

VEP

Visual-evoked potential

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.IRCCS Neuromed, Headache ClinicPozzilliItaly
  2. 2.Department of Medico-Surgical Sciences and BiotechnologiesSapienza University of Rome Polo PontinoLatinaItaly

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