Pregnancy-Associated Breast Cancer

  • BBSG – Brazilian Breast Study Group


Pregnancy-associated breast cancer is defined as breast cancer that is either diagnosed during pregnancy or within 1 year postpartum. However, solely, the first situation presents particularities that interfere in the selection of exams and treatment.


Pregnancy-associated breast cancer Management Chemotherapy Target therapy Prognostic 

Recommended Reading

  1. 1.
    Azim HA Jr, Santoro L, Russell-Edu W, Pentheroudakis G, Pavlidis N, Peccatori FA. Prognosis of pregnancy-associated breast cancer: a meta-analysis of 30 studies. Cancer Treat Rev. 2012;38:834–42. A meta-analysis of 30 retrospective cohorts that observed worse prognosis of breast cancer associated to pregnancy, even after adjusting age and stage groups. In this study, the worst prognosis was related to puerperal or breastfeeding patients. CrossRefGoogle Scholar
  2. 2.
    Cordeiro CN, MD GML. Breast cancer in pregnancy: avoiding fetal harm when maternal treatment is necessary. Breast J. 2017:1–6. The review addresses breast cancer associated to pregnancy treatment and recent updates on surgical and chemotherapeutic treatment safety, regarding oncological and fetal outcomes. Google Scholar
  3. 3.
    Krishna I, Lindsay M. Breast cancer in pregnancy. Obstet Gynecol Clin N Am. 2013;40:559–71. Review article on breast cancer associated to pregnancy, focusing on all stages of treatment. CrossRefGoogle Scholar
  4. 4.
    Loibl S, Han SN, Von Minckwitz G, Bontenbal M, Ring A, Giermek J, et al. Treatment of breast cancer during pregnancy: an observational study. Lancet Oncol. 2012;13:887–96. A 447 patient’s follow-up diagnosed with breast cancer associated to gestation, undergoing standard oncological treatment, which revealed the same disease prognosis as historical series and neonatal complications solely in cases of preterm birth. CrossRefGoogle Scholar
  5. 5.
    Shachar SS, Gallagher K, Mcguire K, Zagar TM, Faso A, Muss HB, et al. Multidisciplinary management of breast cancer during pregnancy. Oncologist. 2017;22:1–11. Multidisciplinary guideline to treat breast cancer associated to pregnancy. CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • BBSG – Brazilian Breast Study Group
    • 1
  1. 1.BBSGSao PauloBrazil

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