Fruit Oils in Kosovo: Chemistry and Functionality

  • Rr. FeriziEmail author
  • Q. Maxhuni


The aim of this chapter is to evaluate phytochemical structure of fruit and essential oils, and their microbiological and antioxidant activities explored by several researchers in Kosovo. Those plants found in Kosovo may be a potential resource of essential oils such are P. terebinthus, S. sylvatica L., J. oxycedrus, B. officinalis (syn. Stachys officinalis), J. communis, and P. mugo Turra.


Phytochemicals Fruits Essential oil composition Microbiological Antioxidant activity Kosovo 



Cation-adjusted Mueller-Hinton broth


Mueller Hinton Broth


Clinical Laboratory Standards Institute


Dimethyl sulfoxide


Deoxyribonucleic acid




Essential oils


Flame ionization detector


Ferric reduction activity potential


Gas chromatography


Gene expression omnibus


Hierarchical cluster analysis


International Union for Conservation of Nature (Red List of Threatened Species)


Kovats Indices


Minimum inhibitory concentration


Methicillin-resistant Staphylococcus Aureus


Mass spectrometer


National Institute of Standards and Technology


Optical density


Principal component analysis


Tryptic soy agar


Tea tree oil


Staphylococcus aureus subsp. aureus strain


  1. Adams, R. (2009). Identification of essential oil components by gas chromatography/mass spectroscopy. Carol Stream: Allured Publishing. isbn:9781932633214.Google Scholar
  2. Adams, R. P., & Tashev, A. N. (2013). The volatile leaf oils of three Juniperus communis varieties from Bulgaria. Phytologia, 95, 302–307.Google Scholar
  3. Adams, R. P., Pandey, R. N., Leverenz, J. W., Dignard, N., Hoegh, K., & Thorfinnsson, T. (2003). Pan-Arctic variation in Juniperus communis: Historical biogeography based on DNA fingerprinting. Biochemical Systematics and Ecology, 31(2), 181–192. Scholar
  4. Agelet, A., & Vallès, J. (2003). Studies on pharmaceutical ethnobotany in the region of Pallars (Pyrenees, Catalonia, Iberian Peninsula). Journal of Ethnopharmacology.. Part III. Medicinal uses of non-vascular plants. (PMID: 12648819). Scholar
  5. Agrawal, O. P., Bharadwaj, S., & Mathur, R. (1980). Antifertility effects of fruits of Juniperus communis. Planta Medica, 40(S 1), 98–101. Scholar
  6. MTI – IPAK (2008). Agriculture and food processing industry. Economic Initiative for Kosova - ECIKS on behalf of IPAK, Prishtine, Kosovo.Google Scholar
  7. Angioni, A., Barra, A., Russo, M. T., Coroneo, V., Dessí, S., & Cabras, P. (2003). Chemical composition of the essential oils of Juniperus from ripe and unripe berries and leaves and their antimicrobial activity. Journal of Agricultural and Food Chemistry, 51(10), 3073–3078. Scholar
  8. Aslan, I., Özbek, H., Kordali, Ş., Çalmaşur, Ö., & Cakir, A (2004). Toxicity of essential oil vapours obtained from Pistacia spp. to the granary weevil, Sitophilus granarius (L.) (Coleoptera: Curculionidae). Zeitschrift für Pflanzenkrankheiten und Pflanzenschutz/Journal of Plant Diseases and Protection 400–407.
  9. Asllani, U. (2002). Esencat e bimeve aromatike e mjekesore te trevave shqiptare (the essences of aromatic and medicinal herbs of Albanian regions). Tirane.
  10. Assimopoulou, A. N., & Papageorgiou, V. P. (2007). Oleoresins from Pistacia species: chemistry and biology. Natural products II. Recent Progress in Medicinal Plants, 18, 145–202.Google Scholar
  11. Bakkali, F., Averbeck, S., Averbeck, D., & Idaomar, M. (2008). Biological effects of essential oils-a review. Food and Chemical Toxicology, 46(2), 446–475. Scholar
  12. Bankova, V., Koeva-Todorovska, J., Stambolijska, T., Ignatova-Groceva, M.D., Todorova, D., Popov, S (1999) Polyphenols in Stachys and Betonica species (Lamiaceae). Zeitschrift für Naturforschung. Section C, 54(11):876–880. Scholar
  13. Barjaktarović, B., Sovilj, M., & Knez, Ž. (2005). Chemical composition of Juniperus communis L. fruits supercritical CO2 extracts: Dependence on pressure and extraction time. Journal of Agricultural and Food Chemistry, 53(7), 2630–2636. Scholar
  14. Barnes, J., Anderson, L. A., & Phillipson, J. D. (2007). Herbal medicines (3rd ed.). London: Pharmaceutical Press. isbn:9780853696230.Google Scholar
  15. Bedi, S., & Vyas, S. P (2008). A handbook of aromatic and essential oil plants: Cultivation, chemistry, processing and uses. In A handbook of aromatic and essential oil plants: Cultivation, chemistry, processing and uses. India: AGROBIOS PublishersGoogle Scholar
  16. Bilusic-Vundac, V., Brantner, A., & Plazibat, M. (2007). Content of polyphenolic constituents and antioxidant activity of some Stachys taxa. Food Chemistry, 1041, 277–1281. Scholar
  17. Boukhatem, M. N., Kameli, A., & Saidi, F. (2013). Essential oil of Algerian rose-scented geranium (Pelargonium graveolens): Chemical composition and antimicrobial activity against food spoilage pathogens. Food Control, 34, 208–213. Scholar
  18. Butkienė, R., Nivinskienė, O., Mockutė, D., Miliūtė, A (2007). Variety of the essential oils composition of wood, needles (leaves), unripe and ripe berries of Juniperus communis var. communis growing wild in Druskininkai district. Chemija 18(3), 35–40.Google Scholar
  19. Carson, C., & Hammer, K. (2011). Chemistry and Bioactivity of Essential Oils. In H. Thormar (Ed.), Lipids and essential oils as antimicrobial agents (pp. 203–238). United Kingdom: John Wiley & Sons.Google Scholar
  20. Cavaleiro, C. (2001). Oleos essenciais de Juniperus de Portugal. Dissertation. University of Coimbra, Portugal.
  21. Couladis, M., Özcan, M., Tzakou, O., & Akgül, A. (2003). Comparative essential oil composition of various parts of the turpentine tree (Pistacia terebinthus L) growing wild in Turkey. Journal of the Science of Food and Agriculture, 83, 136–138. Scholar
  22. Damjanović, B., Skala, D., Baras, J., & Petrović Djakov, D. (2006). Isolation of essential oil and supercritical carbon dioxide extract of Juniperus communis L. fruits from Montenegro. Flavour and Fragrance Journal, 21, 875–880. Scholar
  23. De Laurentis, N., Rosato, A., Milillo, M. A., & Leone, L. (2004). Chemical composition and antifungal activity of Pistacia terebinthus L. aerial part essential oil. Rivista Italiana EPPOS, 38, 11–18.Google Scholar
  24. de Medeiros, P. M., Soldati, G. T., Alencar, N. L., Vandebroek, I., Pieroni, A., Hanazaki, N., et al. (2012). The use of medicinal plants by migrant people: Adaptation, maintenance, and replacement. Evidence-based Complementary and Alternative Medicine, 2012, 807452. Scholar
  25. Derwich, E. L. H. O. U. S. S. I. N. E., & Chabir, R. A. C. H. I. D. A. (2011). Identification of the volatile constituents of the essential oil of Juniperus oxycedrus (Cupressaceae) from the North Centre region of Morocco. Asian Journal of Pharmaceutical and Clinical Research, 4(Suppl 1), 50–54. ISSN- 0974-2441.Google Scholar
  26. Dhifi, W., Mnif, W., Ouerhani, B., & Ghrissi, K. (2012). Chemical composition and antibacterial activity of essential oil from the seeds of Pistacia terebinthus grown in Tunisia. Journal of Essential Oil-Bearing Plants, 15(4), 582–587.CrossRefGoogle Scholar
  27. Durmaz, G., & Gökmen, V. (2011). Changes in oxidative stability, antioxidant capacity and phytochemical composition of Pistacia terebinthus oil with roasting. Food Chemistry, 128, 410–414. Scholar
  28. Duru, M. E., Cakir, A., Kordali, S., Zengin, H., Harmandar, M., Izumi, S., & Hirata, T. (2003). Chemical composition and antifungal properties of essential oils of three Pistacia species. Fitoterapia, 74(1–2), 170–176. Scholar
  29. Essedra (2012). Accessed 19.02.16.
  30. European Pharmacopoeia (2007) 6th edn. EDQM Council of Europe, 7 allée Kastner, CS 30026, F-67081 Strasbourg, France, Vol. 1.
  31. Fernandez, A. M., Camacho, A. M., Fernandez, C., Perez, P., & Altarejos, J. (1998). Preliminary study of the essential oil of Pistacia terebinthus. Ars Pharmaceutica, 39(3–4), 185–191.Google Scholar
  32. Fia, C. (2006). Albanesi, cossovari e molti altri nella scuola di Monteroni D’Arbia. Monticiano: Goree.Google Scholar
  33. Flamini, G., Bader, A., Cioni, P. L., Katbeh-Bader, A., & Morelli, I. (2004). Composition of the essential oil of leaves, galls, and ripe and unripe fruits of Jordanian Pistacia palaestina Boiss. Journal of Agricultural and Food Chemistry, 52, 572–576. Scholar
  34. Gastaldo, P. (1987) Compendio della flora officinale Italiana. Piccin. ISBN:8829905992.Google Scholar
  35. Giner-Larza, E. M., Máñez, S., Giner-Pons, R. M., Recio, M. C., & Rios, J. L. (2000). On the anti-inflammatory and anti-phospholipase A2 activity of extracts from lanostane-rich species. Journal of Ethnopharmacology, 73, 61–69. Scholar
  36. Giner-Larza, E. M., Máñez, S., Recio, M. C., Giner, R. M., Prieto, J. M., Cerdá-Nicolás, M., & Rios, J. L. (2001). Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity. European Journal of Pharmacology, 428, 137–143. Scholar
  37. Gonny, M., Cavaleiro, C., Salgueiro, L., & Casanova, J. (2006). Analysis of Juniperus communis subsp. alpina needle, berry, wood and root oils by combination of GC, GC/MS and 13CNMR. Flavour and Fragrance Journal, 21, 99–106. Scholar
  38. Grujic Jovanovic, S., Skaltsa, H. D., Marin, P., & Sokovic, M. (2004). Composition and antibacterial activity of the essential oil of six Stachys species from Serbia. Flavour and Fragrance Journal, 19, 139–144. Scholar
  39. Guerra Hernandez, E., Lopez Martinez, M., & Villanova, R. G. (1987). Determination by gas chromatography of terpenes in the berries of the species Juniperus oxycedrus L., J. thurifera L. and J. sabina L. Journal of Chromatography, 396, 416–420. Scholar
  40. Hajdari, A., & Mustafa. (2016). Essential oils from Kosovar aromatic plants. Macedonian Pharmaceutical Bulletin, 62(suppl), 467–468. UDC: 633.8:581.135.5(497.115).Google Scholar
  41. Hajdari, A. et al (2009) Total flavonoids, total phenolics and antioxidant activity of betonica officinalis L. from Kosovo. Acta Hortic, 860, 75–80. DOI: 10.17660/ActaHortic.2010.860.8.Google Scholar
  42. Hajdari, A., Mustafa, B., Nebija, D., Widelski, J., Glowniak, K., & Novak, J. (2014a). Essential oil composition and variability of Hypericum perforatum L. from wild population in Kosovo. Currrent Issues Pharmacy and Medical Sciences, 27, 51–54. Scholar
  43. Hajdari, A., Mustafa, B., Gashi, V., Nebija, D., Ibraliu, A., & Novak, J. (2014b). Chemical composition of the essential oils of ripe berries of Juniperus oxycedrus L., growing wild in Kosovo. Biochemical Systematics and Ecology, 57, 90–94. Scholar
  44. Hajdari, A., Mustafa, B., Gashi, V., Nebija, D., Ibraliu, A., & Novak, J. (2014c). Chemical composition of the essential oils of ripe berries of Juniperus oxycedrus L., growing wild in Kosovo. Biochemical Systematics and Ecology, 57, 90–94.CrossRefGoogle Scholar
  45. Hajdari, A., Mustafa, B., Ahmeti, G., Pulaj, B., Lukas, B., Ibraliu, A., & Novak, J. (2015a). Essential oil composition variability among natural populations of Pinus mugo Turra in Kosovo. Springerplus, 4, 828. Scholar
  46. Hajdari, A., Mustafa, B., Ahmeti, G., Pulaj, B., Lukas, B., Ibraliu, A., Stefkov, G., Quave, C. L., & Novak, J. (2015b). Essential oil composition variability among natural populations of Pinus mugo Turra in Kosovo. Springerplus, 4(1), 828. Scholar
  47. Hajdari, A., Mustafa, B., Nebija, D., Miftari, E., Quave, C. L., & Novak, J. (2015c). Chemical composition of Juniperus communis L. Cone essential oil and its variability among wild populations in Kosovo. Chemistry & Biodiversity, 12, 1706–1717. Scholar
  48. Hartwell, J. L. (1982). Plants used against cancer, a survey (p. 154). Lawrence: Quarterman Publications. Scholar
  49. Haziri, A., Faiku, F., Mehmeti, A., Govori, S., Abazi, S., Daci, M., Haziri, I., Bytyqi-Damoni, A., & Mele, A. (2013). Antimicrobial properties of the essential oil of Juniperus Communis (L.) growing wild in east part of Kosovo. American Journal of Pharmacology and Toxicology, 8(3), 128. Scholar
  50. Hörster, H. (1974). Vergleich der Monoterpenfraktionen von Juniperus drupacea und Juniperus oxycedrus. Planta Medica, 26(06), 113–118. Scholar
  51. Ismail, A., Lamia, H., Mohsen, H., & Bassem, J. (2012). Herbicidal potential of essential oils from three Mediterranean trees on different weeds. Current Bioactive Compounds, 8(1), 3–12. Scholar
  52. Ismail, A., Lamia, H., Mohsen, H., Samia, S., & Bassem, J. (2013). Chemical composition and antifungal activity of three Anacardiaceae species grown in Tunisia. Science International, 1, 148–154.CrossRefGoogle Scholar
  53. Ismajli, R., & Kraja, M. (2011). Kosova, Vështrim monografik. Pristina: Akademia e Shkencave dhe e Arteve e Kosovës. isbn:9789951413961.Google Scholar
  54. ISO, the International Organization for Standardization. (2003). Oil of dwarf pine (Pinus mugo Turra) (Vol. 1. ISO no 21093, pp. 1–14). Geneva: International Organization for Standardization.Google Scholar
  55. Kalle, R., & Sõukand, R. (2012). Historical ethnobotanical review of wild edible plants of Estonia (1770s-1960s). Acta Societatis Botanicorum Poloniae, 81(4), 359–370. Scholar
  56. Kartnig, T., Fischer, U., & Bucar, F. (1996). Vegleichende gaschromatographische Untersuchungen an Latschenkieferolen. Scientia Pharmaceutica, 64, 487–496.Google Scholar
  57. Kartnig, T., Fischer, U., & Bucar, F. (1997). Vergleichende gaschromatographische Untersuchungen an Latschenkieferölen. Mitteilun Scientia Pharmaceutica, 65, 289–297.Google Scholar
  58. Kıvçak, B., Akay, S., Demirci, B., & Başer, K. (2004). Chemical composition of essential oils from leaves and twigs of Pistacia lentiscus, Pistacia lentiscus var. chia, and Pistacia terebinthus from Turkey. Pharmaceutical Biology, 42(4–5), 360–366. Scholar
  59. Kordali, S., Cakir, A., Zengin, H., & Duru, M. E. (2003). Antifungal activities of the leaves of three Pistacia species grown in Turkey. Fitoterapia, 74(1–2), 164–167. Scholar
  60. Lamparsky, D., & Klimes, I. (1985). Neue Ergebnisse der Wacholderbeeröl-Analyse im Hinblick auf terpenoide Inhaltsstoffe. Parfümerie und Kosmetik, 66(9), 553–560.Google Scholar
  61. Maillard, M. N., Soum, M. H., Boivin, P., & Berset, C. (1996). Antioxidant activity of barley and malt: Relationship with phenolic content. LWT- Food Science and Technology, 29(3), 238–244. Scholar
  62. Marongiu, B., Porcedda, S., Piras, A., Sanna, G., Murreddu, M., & Loddo, R. (2006). Extraction of Juniperus communis L. ssp. nana Willd. essential oil by supercritical carbon dioxide. Flavour and Fragrance Journal, 21(1), 148–154. Scholar
  63. Matović, M., Bojović, B., & Juscaron, M. (2011). Composition of essential oils from three classes of juniper fruit from Serbia. Journal of Medicinal Plant Research, 5(26), 6160–6163. Scholar
  64. Maxhuni, Q., & Ferizi, Rr. (2018). The state of Kosovo biodiversity 2011–2017. Conference: International ecology 2018 symposium. doi:
  65. Mohagheghzadeh, A., Faridi, P., & Ghasemi, Y. (2010). Analysis of mount atlas mastic smoke: A potential food preservative. Fitoterapia, 81(6), 577–580. Scholar
  66. Obidi, O. F., Adelowotan, A. O., Ayoola, G. A., Johnson, O. O., Hassan, M. O., & Nwachukwu, S. C. U (2013). Antimicrobial activity of orange oil on selected pathogens. Online ISSN: 2321-9122.Google Scholar
  67. Petretto, G. L., Chessa, M., Piana, A., Masia, M. D., Foddai, M., Mangano, G., Culeddu, N., Afifi, F. U., & Pintore, G. (2013). Chemical and biological study on the essential oil of Artemisia caerulescens L. ssp. densiflora (Viv.). Natural Product Research, 27(19), 1709–1715. Scholar
  68. Polat, R., Cakilcioglu, U., & Satıl, F. (2013). Traditional uses of medicinal plants in Solhan (Bingöl-Turkey). Journal of Ethnopharmacology, 148(3), 951–963. Scholar
  69. Potocnik, I., Vukojević, J., Stajic, M., Tanovic, B., & Rekanovic, E. (2010). Sensitivity of Mycogone perniciosa, pathogen of culinary-medicinal button mushroom Agaricus bisporus (J. Lge) Imbach (Agaricomycetideae), to selected fungicides and essential oils. International Journal of Medicinal Mushrooms, 12(1), 91–98. Scholar
  70. Pourmorad, F., Hosseinimehr, S. J., & Shahabimajd, N. (2006). Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. African Journal of Biotechnology, 5(11), 1142–1145. ISSN 1684-5315.Google Scholar
  71. Pulaj, B., Mustafa, B., Nelson, K., Quave, C. L., & Hajdari, A. (2016). Chemical composition and in vitro antibacterial activity of Pistacia terebinthus essential oils derived from wild populations in Kosovo. BMC Complementary and Alternative Medicine, 16(1), 147. Scholar
  72. Raut, J. S., & Karuppayil, S. M. (2014). A status review on the medicinal properties of essential oils. Industrial Crops and Products, 62, 250–264. Scholar
  73. Sánchez-González, L., Vargas, M., González-Martínez, C., Chiralt, A., & Cháfer, M. (2011). Use of essential oils in bioactive edible coatings: A review. Food Engineering Reviews, 3(1), 1–16. Scholar
  74. Sela, F., Karapandzova, M., Stefkov, G., & Kulevanova, S. (2011). Chemical composition of berry essential oils from Juniperus communis L.(Cupressaceae) growing wild in Republic of Macedonia and assessment of the chemical composition in accordance to European Pharmacopoeia. Pharmaceutical Bulletin, 57, 43–51. udc: 582.477-113.55(497.7).Google Scholar
  75. Sirousmehr, A., Arbabi, J., & Asgharipour, M. R. (2014). Effect of drought stress levels and organic manures on yield, essential oil content and some morphological characteristics of sweet basil (Ocimum basilicum). Biology, 8(4), 880–885. ISSN:1995-0756 EISSN:1998-1066.Google Scholar
  76. Stevanovic, T., Garneau, F. X., Jean, F. I., Gagnon, H., Vilotic, D., Petrovic, S., Ruzic, N., & Pichette, A. (2005). The essential oil composition of Pinus mugo Turra from Serbia. Flavour and Fragrance Journal, 20(1), 96–97. Scholar
  77. Swanston-Flatt, S. K., Day, C., Bailey, C. J., & Flatt, P. R. (1990). Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia, 33(8), 462–464. Scholar
  78. Tirillini, B., Pellegrino, R., & Bini, L. M. (2004). Essential oil composition of Stachys sylvatica L. from Italy. Flavour and Fragrance Journal, 19(4), 330–332. Scholar
  79. Topçu, G., Ay, M., Bilici, A., Sarıkürkcü, C., Öztürk, M., & Ulubelen, A. (2007). A new flavone from antioxidant extracts of Pistacia terebinthus. Food Chemistry, 103(3), 816–822. Scholar
  80. Ulukanli, Z., Karabörklü, S., Öztürk, B., Çenet, M., & Balcilar, M. (2014). Chemical composition, antibacterial and insecticidal activities of the essential oil from the Pistacia terebinthus L. Spp. Palaestina (Boiss.)(Anacardiaceae). Journal of Food Processing and Preservation, 38(3), 815–822. Scholar
  81. Usai, M., Pintore, G., Chessa, M., & Tirillini, B. (2006). Essential oil composition of different aerial parts of Pistacia terebinthus L. growing wild in Sardinia. Journal of Essential Oil Research, 18(4), 383–385. Scholar
  82. Valentini, G., Bellomaria, B., Maggi, F., & Manzi, A. (2003). The leaf and female cone oils of Juniperus oxycedrus L. ssp. oxycedrus and J. oxycedrus ssp. macrocarpa (Sibth. et Sm.) Ball. from Abruzzo. Journal of Essential Oil Research, 15(6), 418–421. Scholar
  83. Vundać, V., Maleš, Ž., Plazibat, M., Golja, P., & Cetina-Čižmek, B. (2005). HPTLC determination of flavonoids and phenolic acids in some Croatian Stachys taxa. JPC Journal of Planar Chromatography Modern TLC, 18(104), 269–273. Scholar
  84. Vuuren, S. V., & Viljoen, A. M. (2007). Antimicrobial activity of limonene enantiomers and 1, 8-cineole alone and in combination. Flavour and Fragrance Journal, 22(6), 540–544. Scholar

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.University of Prishtina “Hasan Prishtina”, Faculty of Medicine, Paramedical DepartmentPrishtineKosovo
  2. 2.Kosovo Institute for Nature ProtectionPrishtineKosovo

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