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Cellular Uptake Mechanisms and Detection of Nanoparticle Uptake by Advanced Imaging Methods

  • Kleanthis Fytianos
  • Fabian BlankEmail author
  • Loretta Müller
Chapter
Part of the NanoScience and Technology book series (NANO)

Abstract

The specific mechanism, of uptake of a nanoparticle by a cell and the subcellular localisation are of great importance regarding the potential effect of the nanomaterial inside the cell. In order to study health risks and the potential of a nanoparticle to be used in biomedical applications, cellular internalization has to be investigated in great detail. This chapter highlights most relevant routes of nanoparticle uptake and includes current approaches for the visualization of particle uptake at the nano-level.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Kleanthis Fytianos
    • 1
  • Fabian Blank
    • 1
    Email author
  • Loretta Müller
    • 2
    • 3
  1. 1.Respiratory Medicine, Department of BioMedical Research (DBMR)University of BernBernSwitzerland
  2. 2.University Children’s Hospital BaselBaselSwitzerland
  3. 3.Department of Pediatrics, InselspitalBern University HospitalBernSwitzerland

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