Vertebroplasty and Other Methods of Vertebral Augmentation
Vertebral compression fractures are an important cause of back pain and disability in patients with osteoporosis and spinal neoplasms. Vertebroplasty is a minimally invasive procedure that involves the percutaneous injection of cement into the fractured vertebral body. This procedure is generally offered as a treatment option for a small subset of patients with symptomatic osteoporotic or neoplastic vertebral fractures that result in significant pain and disability.
There is high-quality evidence to treat selected patients with severe pain within 6 weeks of osteoporotic vertebral fracture. There is moderate quality of evidence regarding the effectiveness of these procedures in the treatment of subacute and chronic osteoporotic and neoplastic vertebral compression fractures. Appropriate patient selection combined with careful procedural techniques results in the best patient outcomes. This chapter will outline the historical background and evidence for efficacy and safety and discuss clinical pearls to aid clinicians in optimizing patient selection and procedural outcomes from vertebroplasty.
KeywordsVertebral augmentation Vertebral fracture Vertebroplasty Osteoporosis Cement Percutaneous Pain Cancer Metastases