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The Hip in Muscular Dystrophy

  • Deborah M. Eastwood
Chapter

Abstract

The muscular dystrophies (MD) are a group of inherited conditions characterized by a progressive muscle weakness and increasing disability. The most common and well-known is Duchenne muscular dystrophy (DMD). DMD is essentially the only MD associated with hip problems.

The medical management of DMD has changed over recent years, particularly with the use of steroid medication. This has lengthened life but is associated with other problems that adversely affect quality of life.

Advances have been made in the understanding of dystrophin production in DMD and Becker Muscular Dystrophy. Trials of molecular based therapies including gene replacement via a viral vector have taken place although there are substantial challenges to translation into widespread clinical practice.

Compared to other neuromuscular diseases, hip problems are unusual in DMD and there are no accepted guidelines for the management of hip contractures or hip subluxation/dislocation in this patient group.

Keywords

Duchenne muscular dystrophy Becker muscular dystrophy Dystrophin Hip Scoliosis 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Deborah M. Eastwood
    • 1
    • 2
  1. 1.Great Ormond St. Hospital for ChildrenLondonUK
  2. 2.The Catterall UnitThe Royal National Orthopaedic HospitalStanmoreUK

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