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Abstract

The skeletal system is developing throughout fetal life and continues to develop well into postnatal life. The changes in the skeleton in embryonic and fetal life are dramatic, and the study of the normal histological changes in bone development can be important for understanding abnormalities encountered in such disease states as intrauterine growth restriction, skeletal dysplasia, and metabolic disturbances. This chapter reviews the normal development of the skeletal system and the histological components of the bone throughout gestation.

Keywords

Endochondral ossification Membranous ossification Woven bone Lamellar bone Periosteum Osteoblast Osteoclast 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory MedicineNorthShore University HealthSystemEvanstonUSA

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