Imaging of Musculoskeletal Manifestations Related to Pediatric Hematologic Diseases

  • Sergio Lopes Viana
  • Maria Custódia Machado Ribeiro
  • Bruno Beber Machado


The vast majority of hematologic diseases (either hemoglobinopathies, coagulopathies, or malignancies) lead to some kind of osteoarticular involvement. Such involvement is often responsible either for the clinical presentation or for some of the most disabling features of these conditions, and it is not uncommon for the radiologist to be the one who first suggests the diagnosis. Awareness of the imaging appearance of the main pediatric hematologic diseases is essential in order to avoid diagnostic errors and allow timely institution of treatment. The following topics cover the imaging features of musculoskeletal manifestations in sickle cell disease, thalassemia, hemophilia, and pediatric hematologic malignancies.


Imaging Joints Radiology Children Adolescents Pediatrics Radiographs X-rays Ultrasonography Computed tomography Magnetic resonance imaging Hemoglobinopathy Sickle cell disease Thalassemia Avascular necrosis Osteonecrosis Bone infarct Coagulopathy Hemophilia Hemarthrosis Hematologic malignancy Leukemia Lymphoma 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Sergio Lopes Viana
    • 1
  • Maria Custódia Machado Ribeiro
    • 2
  • Bruno Beber Machado
    • 3
  1. 1.Hospital da Criança de Brasília José Alencar, Hospital Ortopédico e Medicina Especializada (HOME) and Diagnóstico Clínica de Imagens MédicasBrasíliaBrazil
  2. 2.Hospital da Criança de Brasília José AlencarBrasíliaBrazil
  3. 3.Gastren Clínica Médica e Radiológica (Iúna-ES), Clínica Radiológica Med Imagem, Clínica Radiológica Radial, Santa Casa de Misericórdia and Unimed Sul CapixabaCachoeiro de ItapemirimBrazil

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