Glucose, Insulin, and Inner Ear Pathology

  • Pedro Luiz Mangabeira Albernaz
  • Francisco Zuma e Maia
  • Sergio Carmona
  • Renato Valério Rodrigues Cal
  • Guillermo Zalazar


The inner ear has highly complex metabolic mechanisms. The maintenance of the endocochlear potential and of the chemical composition of endolymph is highly dependent on oxygen and glucose. This chapter discusses two mechanisms of reactive hypoglycemia that cause cochlear and vestibular symptoms. The inner ears are very sensitive organs and in many patients are the first to show signs of carbohydrate metabolism disorders. The cochlear and vestibular symptoms resulting from these disorders are very common, can be diagnosed and treated, and are often reversible.


Reactive hypoglycemia Hyperinsulinemia Brush border membrane disease 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Pedro Luiz Mangabeira Albernaz
    • 1
  • Francisco Zuma e Maia
    • 2
  • Sergio Carmona
    • 3
  • Renato Valério Rodrigues Cal
    • 4
  • Guillermo Zalazar
    • 5
  1. 1.Department of OtolaryngologyAlbert Einstein Hospital São PauloBrazil
  2. 2.Otology / NeurotologyClínica MaiaCanoasBrazil
  3. 3.NeurotologyFundación San Lucas para la NeurocienciaRosárioArgentina
  4. 4.Curso de MedicinaCentro Universitário do ParáBelémBrazil
  5. 5.Department of Neurology in Hospital de San LuisFundación San Lucas para la NeurocienciaRosarioArgentina

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