Classical Framework for Case-Driven Design of Advanced Targeted Nanomedical Solution

  • Uche Chude-Okonkwo
  • Reza MalekianEmail author
  • B. T. Maharaj
Part of the Nanomedicine and Nanotoxicology book series (NANOMED)


The development and deployment of ATN solutions require relentless interdisciplinary efforts in order to bring the system and its tremendous promises to reality. The level of the interdisciplinary commitment can encompass diverse fields such as nanotechnology, communication engineering, electronics, medical biology, systems biology, computational biology, synthetic biology, genetic engineering, molecular engineering, molecular/supramolecular chemistry, atomic/molecular physics, biophysics, bioelectronics, signal processing, information theory, advanced mathematics and translational science (Farokhzad and Langer in Adv Drug Deliv Rev 58:1456–1459, 2006, [1]). With this knowledge spread and planning, the design and development/fabrication of an ATN solution for a particular health challenge can be effectively achieved. It is therefore necessary to develop a framework that will serve as a guide for researchers through the design process and the steps in achieving the ATN goal. This exercise will eventually translate the ATN from the paper-based fundamental research, through the experimental stage to clinical reality.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Uche Chude-Okonkwo
    • 1
  • Reza Malekian
    • 1
    Email author
  • B. T. Maharaj
    • 1
  1. 1.Department of Electrical, Electronic and Computer EngineeringUniversity of PretoriaHatfield, PretoriaSouth Africa

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