Recent Advances on Enzymatic Catalysis as a Powerful Tool for the Sustainable Synthesis of Bio-Based Polyesters
The biocatalyzed synthesis of polyesters is a field exploited since the 1980s when the potential of enzymes for catalyzing selective and stereospecific reactions was reported in several breakthrough studies. This chapter focuses on the most recent developments of enzymatic catalysis when applied in the field of bio-based polyester synthesis. A brief introduction summarizes the history and refreshes the memory of the reader on the most relevant reaction mechanisms. Subsequent sections discuss first the possibility of using novel biocatalysts for the synthesis of aliphatic polyesters, moving to polymers where the selectivity of enzymes and their mild reaction conditions are the key of success for producing functional products and ending with aliphatic-aromatic polyesters, highlighting issues and challenges that arose for the polycondensation of these important monomers. Finally, an outlook on the future perspectives and industrialization potential of this technology is given, supporting the ambitions of moving toward a greener polymer chemistry therefore fitting the current needs of moving away from the traditionally used petrochemical monomers.
KeywordsEnzymatic polymerizations Bio-based polyesters Biocatalyzed synthesis Functional polyesters Candida antarctica lipase B (CaLB) Cutinases
Candida antarctica lipase B
Cutinase 1 from Thermobifida cellulosilytica
Dibutyl tin oxide
Ethylene glycol dimethacrylate
CaLB covalently immobilized on epoxy-activated beads
iCut1 covalently immobilized on epoxy-activated beads
Poly(1,4-butylene succinate-co-1,4-butylene itaconate)
Yarrowia lipolytica lipase
Alessandro Pellis thanks the FWF Erwin Schrödinger fellowship (grant agreement J 4014-N34 for financial support).
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