• Shweta Agarwal
  • Peter M. SadowEmail author
  • Xiaoyin “Sara” Jiang
Part of the Practical Anatomic Pathology book series (PAP)


The parathyroid gland is most commonly encountered in the context of hyperparathyroidism as a primary specimen. Difficulties may arise in making the distinction between hyperplasia, adenoma, and carcinoma. The clinical and histologic features of these entities are discussed, as well as potentially useful ancillary studies. A variety of genetic syndromes which may present with parathyroid disease are reviewed.


Hyperparathyroidism Parathyroid gland Endocrine Multiple endocrine neoplasia Adenoma Carcinoma 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Shweta Agarwal
    • 1
  • Peter M. Sadow
    • 2
    Email author
  • Xiaoyin “Sara” Jiang
    • 3
  1. 1.PathologyThe University of Tennessee Health Science CenterMemphisUSA
  2. 2.Head and Neck PathologyMassachusetts General Hospital, Massachusetts Eye & Ear, Pathology Service, Harvard Medical SchoolBostonUSA
  3. 3.Duke Health, Duke University Medical Center, Department of Pathology, Section of Head and Neck and Endocrine PathologyDurhamUSA

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