Oropharynx, Nasopharynx, and Waldeyer Ring

  • Karan SalujaEmail author
  • Danielle Elliott Range
  • Adel K. El-Naggar
Part of the Practical Anatomic Pathology book series (PAP)


The pharynx comprises two anatomic sites, the oropharynx and nasopharynx, which contain mucosal and lymphoid tissues. Both regions are sites of some of the most well-studied viral-associated malignancies, including human papillomavirus-related oropharyngeal carcinomas and Epstein-Barr virus-related nasopharyngeal carcinomas. In this chapter, we will discuss the classification and pathogenesis of the most common carcinomas of the pharynx and recent advances in ancillary testing of these entities.


Nasopharynx Oropharynx Waldeyer ring Benign squamous tumor Human papillomavirus Oropharyngeal carcinoma HPV-associated oropharyngeal squamous cell carcinoma Non-HPV-associated oropharyngeal squamous cell carcinoma Nasopharyngeal carcinoma Nonkeratinizing nasopharyngeal carcinoma Adenocarcinomas of the pharynx Juvenile angiofibroma Hematolymphoid tumors of the pharynx 



No financial support was needed for the preparation of this chapter. There was no conflict of interest.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Karan Saluja
    • 1
    Email author
  • Danielle Elliott Range
    • 2
  • Adel K. El-Naggar
    • 3
  1. 1.The University of Texas, Health Science Center, McGovern Medical School, Department of Pathology and Laboratory MedicineHoustonUSA
  2. 2.Duke Health, Duke University Medical Center, Department of Pathology, Section of Head and Neck and Endocrine PathologyDurhamUSA
  3. 3.The University of Texas MD Anderson Cancer Center, Department of Pathology, Division of Pathology and Laboratory MedicineHoustonUSA

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