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The Role of Environmental Disruptor Chemicals in the Development of Non Communicable Disease

  • Maryam ZareanEmail author
  • Parinaz Poursafa
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1121)

Abstract

The increasing prevalence of non communicable diseases (NCDs) poses main challenges to global public health. Various environmental exposures to different chemicals and pollutants might interact with genetic and epigenetic mechanisms resulting in the development of NCDs. Among these environmental exposures, endocrine disrupting chemicals (EDCs) consist of a group of compounds with potential adverse health effects and the interference with the endocrine system. They are mostly used in food constituents, packaging industries and pesticides. Growing number of in vitro, in vivo, and epidemiological studies documented the link of EDC exposure with obesity, diabetes, and metabolic syndrome, which are the underlying factors for development of NCDs. Prevention of exposure to EDCs and reduction of their production should be underscored in strategies for primordial prevention of NCDs.

Keywords

Endocrine disruptors Non communicable diseases Environment Metabolic disorder Obesity Diabetes 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Environmental Health Department, Environment Research Center, Research Institute for Primordial Prevention of Non Communicable DiseaseIsfahan University of Medical SciencesIsfahanIran

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