Proteases from Endophytic Fungi with Potential Industrial Applications

  • Suchandra Mandal
  • Debdulal BanerjeeEmail author
Part of the Fungal Biology book series (FUNGBIO)


Proteases are enzymes that hydrolyse proteins and polypeptides into smaller constituents. Holding two-thirds of the global enzyme market, proteases are used to execute unique functions in industries of food, textile, detergent, therapeutics and environmental remediation. Fungi have emerged as the most dominant source of proteases due to several cultivational advantages over other sources. Expeditious industrial growth and emerging environment problems necessitate search for novel enzymes from more efficient fungal sources. Endophytic fungi form an uncharted ecological group of fungi with assorted synthesizing potential. Their efficacy has been proven within a short amount of time, as distinguished bioactive secondary metabolites have already been obtained from them. Commercial hydrolases are customarily isolated from soil-borne genera of fungi, but their endophytic counterparts offer a potential alternative, owing to recent findings that endophytes too display the same array of enzymes as do the soil fungi. Prospecting of endophytic fungi for protease production is not only promising, but there also exists the possibility of isolating and characterizing novel proteases that might be suitable alternatives for specialized industries. Several researchers have endorsed this postulate as they have discovered endophytic fungi with optimum protease producing capabilities and novel proteases with projected industrial applications prima facie.


Bioprospecting Bioremediation Endophytic fungi Fermentation Industrial applications Protease 



Authors are thankful to the Council of Scientific and Industrial Research (CSIR), Government of India, for financial support in the form of Junior Research Fellowship to SM and Department of Biotechnology (DBT), New Delhi for financial support.


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Authors and Affiliations

  1. 1.Microbiology and Microbial Biotechnology Laboratory, Department of Botany and ForestryVidyasagar UniversityMidnaporeIndia

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