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Obesity

  • Anjali SharmaEmail author
Chapter

Abstract

Overweight and obesity prevalence rates among HIV-infected persons in western nations are comparable to those in uninfected populations and as high as 65%. Modest weight gain has been reported with HAART use, which may confer additional risk of developing cardiovascular disease and diabetes, particularly in those with greater pre-ART BMI. Visceral adipose tissue (VAT), in both intra-abdominal and epicardial depots, has been implicated as an independent risk factor for conditions such as insulin resistance, diabetes, hepatic steatosis, dyslipidemia, and hypertension and more recently in the development of subclinical atherosclerosis and adverse cardiovascular outcomes. Therapeutic strategies aimed at reducing VAT may hold particular promise in reducing disease in aging HIV-infected persons, in whom disorders of body composition and premature cardiovascular disease develop frequently.

Keywords

Obesity Overweight Central obesity Visceral adipose tissue Epicardial adipose tissue 

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Divisions of General Internal Medicine and Infectious Diseases, Department of MedicineAlbert Einstein College of MedicineBronxUSA

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