Medical and Surgical Management of Colorectal Cancer Patients Presenting with Haemostatic Disorders
Maintaining haemostasis during surgery is essential to preserve physiologic functions for the patient, provide the surgeon with the ability to see the operative field and promote successful wound management and patient outcomes. In addition, effective surgical haemostasis also results in fewer blood transfusions, decreased operating time and reduced morbidity and mortality.
The normal coagulation pathway represents a balance between the procoagulant pathway that is responsible for clot formation and the mechanisms that inhibit the same beyond the injury site. Imbalance of the coagulation system may occur in the perioperative period or during critical illness, which may be secondary to numerous factors leading to a tendency of either thrombosis or bleeding. A multidisciplinary approach is essential, and the surgical team must closely liaise with the haematology and anaesthetic team.
This chapter describes the pathophysiology of the haemostasis and the most common disorders encountered in clinical practice in emergency surgery.
KeywordsColorectal cancer Emergency surgery Haemostatic disorders Bleeding disorders
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