Invasive Fungal Diseases of the Skull Base

  • Manogaran Ravi Sankar
  • Mathialagan Arulalan
  • Amit K. Keshri
  • Arun K. Srivastava
  • Awadhesh K. Jaiswal
  • Sanjay Behari


Skull base fungal pathologies present with headache, nasal symptoms, orbital symptoms, cranial nerve palsy and paresis. Isolated skull base involvement is rare; commonly, skull base is involved by the lesion spreading from the adjacent paranasal sinuses. Vital structures like the orbit, optic nerve, internal carotid artery, pituitary gland, cavernous sinus and cranial nerves may often be involved. This chapter gives the overview of various types of skull base fungal diseases and their management principles.


Skull base Fungal infection Aspergillosis Mucormycosis Classification Management 



Allergic fungal rhinosinusitis


Acute invasive skull base fungal disease


Chronic invasive granulomatous fungal disease


Chronic invasive skull base fungal disease


Cerebrospinal fluid

CT scan

Computed tomographic scan


Food and Drug Administration

Ig E

Immunoglobulin E


Magnetic resonance imaging


Polymerase chain reaction


Weighted images


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Manogaran Ravi Sankar
    • 1
  • Mathialagan Arulalan
    • 1
  • Amit K. Keshri
    • 1
  • Arun K. Srivastava
    • 2
  • Awadhesh K. Jaiswal
    • 2
  • Sanjay Behari
    • 2
  1. 1.Division of Neuro-otology, Department of NeurosurgerySanjay Gandhi Postgraduate Institute of Medical SciencesLucknowIndia
  2. 2.Department of NeurosurgerySanjay Gandhi Postgraduate Institute of Medical SciencesLucknowIndia

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