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The Role of Biomarkers in Psychiatry

  • Madia Lozupone
  • Maddalena La Montagna
  • Francesca D’Urso
  • Antonio Daniele
  • Antonio Greco
  • Davide Seripa
  • Giancarlo Logroscino
  • Antonello Bellomo
  • Francesco PanzaEmail author
Chapter
First Online:
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1118)

Abstract

Psychiatric illnesses are cognitive and behavioral disorders of the brain. At present, psychiatric diagnosis is based on DSM-5 criteria. Even if endophenotype specificity for psychiatric disorders is discussed, it is difficult to study and identify psychiatric biomarkers to support diagnosis, prognosis, or clinical response to treatment. This chapter investigates the innovative biomarkers of psychiatric diseases for diagnosis and personalized treatment, in particular post-genomic data and proteomic analyses.

Keywords

Proteomics Biomarker Post-genomic diagnostics Psychiatric disease Epigenetics Microbiota Lifestyle Depressive disorder Schizophrenia Bipolar disorder 
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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Madia Lozupone
    • 1
  • Maddalena La Montagna
    • 2
  • Francesca D’Urso
    • 2
  • Antonio Daniele
    • 3
    • 4
  • Antonio Greco
    • 5
  • Davide Seripa
    • 5
  • Giancarlo Logroscino
    • 1
    • 6
  • Antonello Bellomo
    • 2
  • Francesco Panza
    • 1
    • 5
    • 6
    Email author
  1. 1.Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense OrgansUniversity of Bari Aldo MoroBariItaly
  2. 2.Psychiatric Unit, Department of Clinical and Experimental MedicineUniversity of FoggiaFoggiaItaly
  3. 3.Institute of NeurologyCatholic University of Sacred HeartRomeItaly
  4. 4.Fondazione Policlinico Universitario A. Gemelli IRCCSRomeItaly
  5. 5.Geriatric Unit, Fondazione IRCCS Casa Sollievo della SofferenzaFoggiaItaly
  6. 6.Department of Clinical Research in NeurologyUniversity of Bari Aldo MoroLecceItaly

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