The diameter of instruments used in transplantation is of decisive importance because of the influence of the diameter of the transplanted fat particles on the result of the transplantation and the aesthetic result. Since 2005, new types of cannulas have been developed for the harvesting and the grafting of very small fat particles into the facial region. Blunt cannulas of the size 16G, 19G, and 22G are recommended for layers under the skin up to 25G fine needles. Into the skin nanofat grafting is generally carried out in connection with a microfat grafting of the layer lying above it directly into the dermis. The treated patients become normal in appearance after just 3 days, and the final healing result is achieved after a period of 4 weeks. The suitable areas are the forehead, periorbital and brow and temple regions, lower eyelids, middle part of the face, lips, perioral region, and the lower third part of the face including the chin and jaw line.
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