Systemic and Dismetabolic Disorders



Several systemic or metabolic disorders may cause an impairment of cerebral functions. Neuroimaging investigations are often not sensitive enough to appropriately evaluate these clinical conditions. The EEG represents therefore a useful method for assessing brain functional activity, to support clinical diagnosis and to monitor follow-up (neuromonitoring). In systemic and metabolic disorders, EEG changes reflect the diffuse cerebral impairment and may detect negative prognostic factors. Widespread EEG slowing sometimes associated with epileptiform activity is a typical pattern encountered in these conditions; however it is neither pathognomonic nor specific of a certain etiology. EEG can also demonstrate the improvement of cerebral function following therapy of the underlying disorder.


Acute porphyria Cardiorespiratory disease Disorders of glucose metabolism Eclampsia Electrolyte disturbances Liver disease Renal disease Thyroid and hormonal disorders 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Neurosciences, Biomedicine and Movement SciencesUniversity of VeronaVeronaItaly
  2. 2.Department of NeurologyHospital Franz TappeinerMeranoItaly
  3. 3.Department of Human NeurosciencesSapienza University of RomeRomeItaly

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