Local Therapies

  • Rachel Grossmann
  • Zvi Ram
  • Michael A. Vogelbaum
  • E. Antonio Chiocca
  • Manfred Westphal
  • Jörg-Christian Tonn
  • Friedrich Kreth
  • Niklas Thon


Local therapies in the context of cranial tumor encompass the concept of local application or local delivery, respectively. Apart from surgical resection which is the most obvious form of local therapy, radiation is also targeted to the field of the tumor, the residual tumor, or the resection cavity but is dealt within the respective chapters as is the surgical aspect. Here the focus is on therapies which are applied at the time of surgery either into the resection cavity or into the surrounding tissue or are delivered by surgical means like catheters into tumor tissue without resection.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Rachel Grossmann
    • 1
  • Zvi Ram
    • 1
  • Michael A. Vogelbaum
    • 2
  • E. Antonio Chiocca
    • 3
  • Manfred Westphal
    • 4
  • Jörg-Christian Tonn
    • 5
  • Friedrich Kreth
    • 6
  • Niklas Thon
    • 6
  1. 1.Department of NeurosurgeryTel Aviv Sourasky Medical Center, TASMCTel AvivIsrael
  2. 2.Rose Ella Burkhardt Brain Tumor and NeuroOncology CenterCleveland Clinic Lerner College of Medicine of Case Western Reserve UniversityClevelandUSA
  3. 3.Department of NeurosurgeryBrigham and Women’s Hospital, Harvard Medical SchoolBostonUSA
  4. 4.Department of NeurosurgeryUniversity of Hamburg, University Hospital Eppendorf, HamburgHamburgGermany
  5. 5.Department of NeurosurgeryUniversity Hospital Ludwig Maximilian University MunichMunichGermany
  6. 6.Department of NeurosurgeryLMU, Campus GrosshadernMunichGermany

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